Chou Y.-H.Wang H.-Y.MIN-SHU HSIEH2020-03-052020-03-0520111607-551Xhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-79953775113&doi=10.1016%2fj.kjms.2010.12.010&partnerID=40&md5=088724a25f2d99e2555d927bdd2ebed9https://scholars.lib.ntu.edu.tw/handle/123456789/470816Kayexalate (sodium polystyrene sulfonate) is a cation-exchange resin used to treat patients with hyperkalemia. Concomitant administration of kayexalate and sorbitol may induce gastrointestinal injury, which is potentially lethal. However, this well-documented complication is often underrecognized both clinically and pathologically. We propose a typical case along with colonoscopic photos and microscopic pictures. Additionally, we also present a review of the literature on this rare drug-induced side effect. Copyright ? 2011, Elsevier Taiwan LLC. All rights reserved.[SDGs]SDG3cefmetazole; hemoglobin; polystyrenesulfonate sodium; sorbitol; abdominal infection; adult; anemia; article; case report; colon disease; colon necrosis; colonoscopy; dyspnea; emergency ward; endoscopic biopsy; follow up; gastrointestinal disease; hematochezia; human; hyperkalemia; leukocytosis; male; outcome assessment; pallor; Administration, Oral; Adult; Colon; Colonoscopy; Crystallization; Humans; Male; Necrosis; Polystyrenes; Sorbitol; Staining and Labelingjournal article10.1016/j.kjms.2010.12.010214638392-s2.0-79953775113