Increased HIF-1α expression in T cells and associated with enhanced Th17 pathway in systemic lupus erythematosus

Liao, Hsiu-JungHsiu-JungLiaoCHING-LIANG CHUWang, Szu-ChiehSzu-ChiehWangLee, Hua-YiHua-YiLeeWu, Chien-ShengChien-ShengWu2024-03-272024-03-272022-120929-6646https://scholars.lib.ntu.edu.tw/handle/123456789/641472Recent emerging evidence indicates that dysfunction of metabolic remodeling underlies aberrant T cell immune responses in systemic lupus erythematosus (SLE). This study was undertaken to investigate the expression of HIF-1α, a regulator of metabolic reprogramming, in T cells from SLE.enCD4 T cells; HIF-1α; Metabolic reprogramming; SLE; Th17Increased HIF-1α expression in T cells and associated with enhanced Th17 pathway in systemic lupus erythematosusjournal article10.1016/j.jfma.2022.05.003355991042-s2.0-85130560913https://api.elsevier.com/content/abstract/scopus_id/85130560913