Jiang, LiLiJiangKIEN-VOON KONGHe, SailingSailingHeYong, Ken-TyeKen-TyeYong2022-12-192022-12-192022-112192-6506https://scholars.lib.ntu.edu.tw/handle/123456789/626587Observing a Goos-Hänchen (GH) shift of the incident light beam provides a simple and convenient method of detecting fast phase variations without the need for cumbersome direct phase measurements. Here, we show that few-monolayers-thick van der Waals structures (WS<sub>2</sub> , MoSe<sub>2</sub> and graphene) nano-engineered onto a plasmonic surface can enhance the phase variation sensitivity to analyte presence, leading to more than 3 orders of magnitude increase in the Goos-Hänchen shift (ca. 886 mm/RIU for a WS<sub>2</sub> /graphene/Au multilayer). The detection limit is evaluated to be as low as 0.1 aM (6.7 pg/mL) for bovine serum albumin protein with molecular weight of 67 kDa and 1 fM (24.4 ng/mL) for biotin (244 Da) molecules.en2D materials; Goos-Hähnchen shift; biosensing; surface plasmon resonancePlasmonic Biosensing with Nano-Engineered Van der Waals Interfacesjournal article10.1002/cplu.202200221363287752-s2.0-85142611666WOS:000878356300001https://api.elsevier.com/content/abstract/scopus_id/85142611666