John, Antony Jasmine VincentAntony Jasmine VincentJohnAlagarsamy, SaranvigneshSaranvigneshAlagarsamyChen, Tse-WeiTse-WeiChenChen, Shen-MingShen-MingChenDisouza, Francis Packiaraj DonFrancis Packiaraj DonDisouzaYING-CHIH LIAOSengodan, SivaprakashSivaprakashSengodan2026-01-152026-01-152025-12-1009258388https://www.scopus.com/record/display.uri?eid=2-s2.0-105024887763&origin=resultslisthttps://scholars.lib.ntu.edu.tw/handle/123456789/735356Ensuring environmental safety and protecting human health from sulfonamide residues in pharmaceuticals, animal-derived products, and water sources remains a major challenge. In this study, a high-performance dual-mode electrochemical sensor based on a ZnMn2O4/B-GCN nanocomposite was developed for the sensitive and selective detection of sulfisoxazole (SFXZ). The nanocomposite was characterized by spectroscopic, microscopic techniques and exhibited excellent electrocatalytic activity under both amperometric and differential pulse voltammetry (DPV) modes. The sensor achieved wide linear ranges of 0.001–93.39 µM (amperometry) and 0.001–137 µM (DPV), with detection limits of 0.0096 µM and 0.002 µM. It also demonstrated strong reproducibility, stability, and high recovery in real-sample analysis. These results highlight the potential of the developed sensor for trace-level sulfonamide detection and practical applications in food safety and environmental monitoring.falseDual-mode sensingElectrochemical sensorFood safety monitoringSulfisoxazoleZnMn2O4/B-GCN nanocomposite[SDGs]SDG2journal article10.1016/j.jallcom.2025.1852562-s2.0-105024887763