Lu, Chieh-HsienChieh-HsienLuShiau, Chung-WaiChung-WaiShiauYUNG-CHI CHANGHSIU-NI KUNGJUI-CHING WULim, Chui-HianChui-HianLimYeo, Hui-HuiHui-HuiYeoChang, Han-ChuHan-ChuChangChien, Han-ShengHan-ShengChienHuang, Sheng-HsuanSheng-HsuanHuangHung, Wei-KangWei-KangHungWei, Jun-RongJun-RongWeiHAO-CHIEH CHIU2021-06-242021-06-242021-04-140305-74531460-2091https://scholars.lib.ntu.edu.tw/handle/123456789/566142In the past few decades, multiple-antibiotic-resistant Staphylococcus aureus has emerged and quickly spread in hospitals and communities worldwide. Additionally, the formation of antibiotic-tolerant persisters and biofilms further reduces treatment efficacy. Previously, we identified a sorafenib derivative, SC5005, with bactericidal activity against MRSA in vitro and in vivo. Here, we sought to elucidate the resistance status, mode of action and anti-persister activity of this compound.en[SDGs]SDG3journal article10.1093/jac/dkab11433855344https://scholars.lib.ntu.edu.tw/handle/123456789/563415