Renn T.-Y.Yang C.-P.UN-IN WUChen L.-Y.Mai F.-D.Tikhonova M.A.Amstislavskaya T.G.Liao W.-C.Lin C.-T.Liu Y.-C.Chang H.-M.2022-02-152022-02-1520221385-8947https://www.scopus.com/inward/record.uri?eid=2-s2.0-85113603543&doi=10.1016%2fj.cej.2021.131626&partnerID=40&md5=673779524bf34b28b831e7b7a23e55ffhttps://scholars.lib.ntu.edu.tw/handle/123456789/594583Melatonin is a lipophilic antioxidant generally dissolved in organic solvent before delivery. However, the presence of organics may severely depress the functional effects of melatonin. By rendering deionized water (DIW) flow through gold nano-particles uAnti-oxidative effects; Anti-viral function; Biomedical application; Hepatic bioenergetics; Melatonin; Plasmon-activated water[SDGs]SDG3Enzyme activity; Hormones; Hydrogen bonds; Medical applications; Nanoparticles; Organic solvents; Solubility; Surface plasmon resonance; Viruses; Activated water; Anti oxidative activity; Anti-oxidative effect; Anti-viral function; Biomedical applicationsWater composed of reduced hydrogen bonds activated by localized surface plasmon resonance effectively enhances anti-viral and anti-oxidative activities of melatoninjournal article10.1016/j.cej.2021.1316262-s2.0-85113603543