蔡偉博2006-07-252018-06-282006-07-252018-06-282004-11-02http://ntur.lib.ntu.edu.tw//handle/246246/9390從以前在關節軟骨修補的組織工程研究中，瞭解到要有達到成功的組織工程產品，除 了軟骨細胞、基材和生長因子外，物理性的刺激也可以增加成功產品的機會，不過這方面 的研究非常少。本研究計畫的目的在探討在機械性壓縮對於關節軟骨組織工程的影響。目 前已經完成彈性可分解高分子的合成、組織工程用鷹架的製備，可壓縮式生物反應器的設 計與製作，軟骨細胞的分離與培養，生化分析方法的建立。From previous researches related to articular cartilage tissue engineering, we understand that beside chondrocytes, scaffolds and growth factors, mechanical stimulus is also a key element to successful tissue engineering products. However, the related studies are scarce. The goal of this project is to study the effects of mechanical compression on articular cartilage tissue engineering. We already finished the synthesis of elastic biodegradable polymers, the fabrication of tissue engineering scaffolds, the design and the construction of compressible bioreactors, isolation and culture of chondrocytes, and development of biochemical assays.application/pdf83667 bytesapplication/pdfzh-TW國立臺灣大學化學工程學系暨研究所軟骨細胞關節軟骨組織工程彈性可分解高分子可壓縮式生物反應器reporthttp://ntur.lib.ntu.edu.tw/bitstream/246246/9390/1/922214E002035.pdf