林瑞雄2006-07-252018-06-292006-07-252018-06-291999-07-31http://ntur.lib.ntu.edu.tw//handle/246246/4667研究顯示台灣地區青少年肥胖盛行率 有逐漸上昇之情形，而肥胖青少年易持續 維持至肥胖成人，因此青少年肥胖的健康 問題必需正視及深入瞭解。本研究的主要 目的是利用雙能X 光攝影法測量正常與肥 胖青少年身體脂肪含量及分佈之差異，並 比較肥胖青少年血液中生化代謝指標及纖 瘦蛋白濃度等與正常體位青少年的差異。 自民國87 年8 月至88 年3 月間抽樣收集 台北市2 所國中及1 所高中男女青少年共 317 人，進行問卷調查、血液生化值及體脂 肪含量測定等。結果發現：(1)肥胖組青少 年其體重、BMI 、腰圍、臀圍及腰臀比皆明 顯大於正常體重組，而年齡及身高則無明 顯差異；(2)肥胖組青少年其血液中膽固 醇、三酸甘油酯、尿酸、胰島素及纖瘦蛋 白值明顯高於正常體重組，而高密度脂蛋 白則低於正常體重組，其中纖瘦蛋白值女 性(肥胖23.2 +9.7 ，正常13.3 +7.5ng/ml) 明顯高於男性(肥胖10.5 +6.7 ，正常4.1+4.3ng/ml)；(3)肥胖青少年之身體脂肪 比例、脂肪總重量及局部脂肪重量等皆明 顯比正常體重青少年增加，且其腹部對總 脂肪重量之比例也比較高；(4)以纖瘦蛋白 值為依變數，進行多變項直線迴歸分析， 發現年齡、性別、胰島素及體脂肪重量皆 有統計顯著(p<0.01)獨立的影響。本研究 顯示肥胖青少年的健康問題與成人肥胖相 似，其將來罹患心血管疾病的危險性可能 較正常體重之青少年高，因此建議衛生及 醫療單位必須正視並應及早介入青少年肥 胖的健康問題。The prevalence of obesity during adolescence in Taiwan increases gradually. Adolescent obesity is inclined to persisting into adult obesity, which has been well known for association with diabetes, hypertension, hyperlipidemia and several kinds of cancer. The body composition was analyzed with dual-energy X-ray absorptiometry (DEXA) in this study. Total 317 high school students were recruited from August 1998 to March 1999. The results showed that, (1) body weight, BMI, waist and hip circumferences, and waist-hip ratio were higher in obese than normal adolescents, (2) serum cholesterol, triglycerides, uric acid, fasting insulin and leptin levels were higher in obese than normal adolescents, but HDL was lower, (3) leptin levels were much higher in the females (obese 23.2 + 9.7, normal 13.3 + 7.5ng/ml) than males (obese 10.5 + 6.7,normal 4.1 + 4.3ng/ml), (4) elevated body fat percentage, total and regional fat weight were also noted in obese adolescents, and (5) age, sex, total body fat weight, and insulin level affected independently serum leptin levels through multiple linear regression analysis. The metabolic abnormalities found in obese adolescents seem to be similar in obese adults in our study. The issue on adolescent obesity should be stressed in future studies. In addition, the obese adolescents should be treated as soon as possible.application/pdf46791 bytesapplication/pdfzh-TW國立臺灣大學公共衛生學院預防醫學研究所雙能X光攝影法身體脂肪纖瘦蛋白DEXABody fatLeptin[SDGs]SDG3reporthttp://ntur.lib.ntu.edu.tw/bitstream/246246/4667/1/882314B002248.pdf