JIN-MING WUYAO-MING WUCHIH-YUAN LEEHSIU-PO WANGMING-TSAN LIN2022-01-072022-01-0720120172-6390https://www.scopus.com/inward/record.uri?eid=2-s2.0-84863237739&doi=10.5754%2fhge10040&partnerID=40&md5=a7285a5f85d13aa1e2c54b2134725339https://scholars.lib.ntu.edu.tw/handle/123456789/591855Background/Aims: The role of laparoscopic cholecystectomy for patients with acute cholecystitis and symptoms for >3 days is debated. Our purpose was to compare the results of laparoscopic cholecystectomy in patients with acute cholecystitis and symptoms for ?3 days and >3 days. Methodology: Sixty patients with acute cholecystitis had a laparoscopic cholecystectomy performed by the same surgeon. There were 39 patients in the short group (symptoms ?3 days) and 21 patients in the long group (symptoms >3 days). Demographic data, surgical findings and clinical results were analyzed. Results: There were no significant differences in age, gender, comorbidities, abnormal liver function tests, white bile, gallbladder empyema, blood loss, conversion rate, postoperative hospital stay or complication rates between the groups. The mean duration of acute cholecystitis was 1.9 days in the short group and 5.3 days in the long group (p<0.0001). The long group had a longer operating time (p=0.004) and a higher rate of subhepatic drains (p=0.014). Conclusions: Laparoscopic cholecystectomy is a safe and feasible procedure for patients with acute cholecystitis when the duration of symptoms is >3 days, however, a higher conversion rate is seen for acute chronic cholecystitis. ? H.G.E. Update Medical Publishing S.A.[SDGs]SDG3acute cholecystitis; article; bile composition; cholecystectomy; comorbidity; controlled study; disease duration; empyema; female; gallbladder disease; human; ileus; length of stay; liver abscess; liver function test; major clinical study; male; operation duration; outcome assessment; patient safety; percutaneous drainage; postoperative hemorrhage; priority journal; subhepatic abscess; surgical infection; Adult; Aged; Chi-Square Distribution; Cholecystectomy, Laparoscopic; Cholecystitis, Acute; Feasibility Studies; Female; Humans; Male; Middle Aged; Patient Safety; Patient Selection; Retrospective Studies; Risk Assessment; Risk Factors; Taiwan; Time Factors; Treatment Outcomejournal article10.5754/hge10040222515162-s2.0-84863237739