De Luca, GiuseppeGiuseppeDe LucaAlgowhary, MagdyMagdyAlgowharyUguz, BeratBeratUguzOliveira, Dinaldo CDinaldo COliveiraGanyukov, VladimirVladimirGanyukovZimbakov, ZanZanZimbakovCercek, MihaMihaCercekOkkels Jensen, LisetteLisetteOkkels JensenLoh, Poay HuanPoay HuanLohCalmac, LucianLucianCalmacRoura I Ferrer, GerardGerardRoura I FerrerQuadros, AlexandreAlexandreQuadrosMilewski, MarekMarekMilewskiScotto Di Uccio, FortunatoFortunatoScotto Di Ucciovon Birgelen, ClemensClemensvon BirgelenVersaci, FrancescoFrancescoVersaciTen Berg, JurrienJurrienTen BergCasella, GianniGianniCasellaWong Sung Lung, AaronAaronWong Sung LungKala, PetrPetrKalaDíez Gil, José LuisJosé LuisDíez GilCarrillo, XavierXavierCarrilloDirksen, MauritsMauritsDirksenBecerra-Munoz, Victor MVictor MBecerra-MunozKang-Yin Lee, MichaelMichaelKang-Yin LeeJuzar, Dafsah ArifaDafsah ArifaJuzarde Moura Joaquim, RodrigoRodrigode Moura JoaquimDe Simone, CiroCiroDe SimoneMilicic, DavorDavorMilicicDavlouros, PeriklisPeriklisDavlourosBakraceski, NikolaNikolaBakraceskiZilio, FilippoFilippoZilioDonazzan, LucaLucaDonazzanKraaijeveld, AdriaanAdriaanKraaijeveldGalasso, GennaroGennaroGalassoArpad, LuxLuxArpadMarinucci, LuciaLuciaMarinucciGuiducci, VincenzoVincenzoGuiducciMenichelli, MaurizioMaurizioMenichelliScoccia, AlessandraAlessandraScocciaYamac, Aylin HaticeAylin HaticeYamacUgur Mert, KadirKadirUgur MertFlores Rios, XacobeXacobeFlores RiosKovarnik, TomasTomasKovarnikKidawa, MichalMichalKidawaMoreu, JosèJosèMoreuFlavien, VincentVincentFlavienFabris, EnricoEnricoFabrisLozano Martínez-Luengas, IñigoIñigoLozano Martínez-LuengasBoccalatte, MarcoMarcoBoccalatteBosa Ojeda, FranciscoFranciscoBosa OjedaArellano-Serrano, CarlosCarlosArellano-SerranoCaiazzo, GianlucaGianlucaCaiazzoCirrincione, GiuseppeGiuseppeCirrincioneHSIEN-LI KAOSanchis Forés, JuanJuanSanchis ForésVignali, LuigiLuigiVignaliPereira, HelderHelderPereiraManzo-Silbermann, StephaneStephaneManzo-SilbermannOrdoñez, SantiagoSantiagoOrdoñezArat Özkan, AlevAlevArat ÖzkanScheller, BrunoBrunoSchellerLehtola, HeidiHeidiLehtolaTeles, RuiRuiTelesMantis, ChristosChristosMantisAntti, YlitaloYlitaloAnttiBrum Silveira, João AntónioJoão AntónioBrum SilveiraBessonov, IvanIvanBessonovZoni, RodrigoRodrigoZoniSavonitto, StefanoStefanoSavonittoKochiadakis, GeorgeGeorgeKochiadakisAlexopoulos, DimitriosDimitriosAlexopoulosUribe, Carlos ECarlos EUribeKanakakis, JohnJohnKanakakisFaurie, BenjaminBenjaminFaurieGabrielli, GabrieleGabrieleGabrielliGutierrez Barrios, AlejandroAlejandroGutierrez BarriosBachini, Juan PabloJuan PabloBachiniRocha, AlexAlexRochaTam, Frankie Chor-CheungFrankie Chor-CheungTamRodriguez, AlfredoAlfredoRodriguezLukito, Antonia AnnaAntonia AnnaLukitoBellemain-Appaix, AnneAnneBellemain-AppaixPessah, GustavoGustavoPessahCortese, GiulianaGiulianaCorteseParodi, GuidoGuidoParodiBurgadha, Mohammed AbedMohammed AbedBurgadhaKedhi, ElvinElvinKedhiLamelas, PabloPabloLamelasSuryapranata, HarryHarrySuryapranataNardin, MatteoMatteoNardinVerdoia, MonicaMonicaVerdoia2023-03-092023-03-092022-10-120003-3197https://scholars.lib.ntu.edu.tw/handle/123456789/629090SARS-Cov-2 has been suggested to promote thrombotic complications and higher mortality. The aim of the present study was to evaluate the impact of SARS-CoV-2 positivity on in-hospital outcome and 30-day mortality in ST-segment elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PCI) enrolled in the International Survey on Acute Coronary Syndromes ST-segment elevation Myocardial Infarction (ISACS-STEMI COVID-19 registry. The 109 SARS-CoV-2 positive patients were compared with 2005 SARS-CoV-2 negative patients. Positive patients were older (P = .002), less often active smokers (P = .002), and hypercholesterolemic (P = .006), they presented more often later than 12 h (P = .037), more often to the hub and were more often in cardiogenic shock (P = .02), or requiring rescue percutaneous coronary intervention after failed thrombolysis (P < .0001). Lower postprocedural Thrombolysis in Myocardial Infarction 3 flow (P = .029) and more thrombectomy (P = .046) were observed. SARS-CoV-2 was associated with a significantly higher in-hospital mortality (25.7 vs 7%, adjusted Odds Ratio (OR) [95% Confidence Interval] = 3.2 [1.71-5.99], P < .001) in-hospital definite in-stent thrombosis (6.4 vs 1.1%, adjusted Odds Ratio [95% CI] = 6.26 [2.41-16.25], P < .001) and 30-day mortality (34.4 vs 8.5%, adjusted Hazard Ratio [95% CI] = 2.16 [1.45-3.23], P < .001), confirming that SARS-CoV-2 positivity is associated with impaired reperfusion, with negative prognostic consequences.enSTEMI; outcome; thrombosis[SDGs]SDG3journal article10.1177/00033197221129351362221892-s2.0-85144019096WOS:000866193900001https://api.elsevier.com/content/abstract/scopus_id/85144019096