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2 morpholino 8 phenylchromone; biological marker; bortezomib; immunoglobulin enhancer binding protein; proteasome; protein kinase b; rapamycin; small interfering rna; antineoplastic agent; boronic acid derivative; bortezomib; pyrazine derivative; animal experiment; animal model; animal tissue; apoptosis; article; cancer cell culture; cancer inhibition; cell cycle arrest; cell cycle g2 phase; cell cycle m phase; cell viability; controlled study; dose response; down regulation; enzyme activity; human; human cell; ic 50; liver cell carcinoma; male; mouse; nonhuman; priority journal; protein targeting; sensitivity analysis; signal transduction; animal; cell culture; cell cycle; drug antagonism; drug effect; drug screening; flow cytometry; genetics; liver cell carcinoma; liver tumor; metabolism; nude mouse; pathology; western blotting; animals; antineoplastic agents; apoptosis; blotting, western; boronic acids; carcinoma, hepatocellular; cell cycle; down-regulation; flow cytometry; humans; liver neoplasms; male; mice; mice, nude; nf-kappa b; proteasome endopeptidase complex; proto-oncogene proteins c-akt; pyrazines; tumor cells, cultured; xenograft model antitumor assays
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