研究成果


第 1 到 66 筆結果，共 66 筆。

公開日期標題作者來源出版物scopusWOS全文
12024Design, synthesis, and anti-cancer evaluation of C-14 arylcarbamate derivatives of andrographolideYang, Tzu-Ching; Chiang, Yun-Jou; Chiang, Po-Yu; Chen, Han-Yu; Zhuang, Kai-Ru; Wang, Yu-Chia; Lin, Chao-Hsiung; LEE-CHIANG LO ; Fu, Shu-LingBioorganic & medicinal chemistry
22023Development of fluorous boronic acid catalysts integrated with sulfur for enhanced amidation efficiencyFridianto, Kevin Timothy; Wen, Ya-Ping; LEE-CHIANG LO ; Lam, YulinRSC advances00
32022Versatile Azido-Functionalized Carbon Dots for Cancer Cell ImagingLee, HY; Chiang, PY; Wu, HJ; Wang, TY; Yang, TC; Cheng, Wei-Chieh; LEE-CHIANG LO ; WEI-SSU LIAO ACS APPLIED NANO MATERIALS00
42020Andrographolide and its fluorescent derivative inhibit the main proteases of 2019-nCoV and SARS-CoV through covalent linkageShi, T.-H.; Huang, Y.-L.; Chen, C.-C.; Pi, W.-C.; Hsu, Y.-L.; Lo, L.-C.; Chen, W.-Y.; Fu, S.-L.; Lin, C.-H.; LEE-CHIANG LO Biochemical and Biophysical Research Communications8166
52020Rapid Synthesis of a Natural Product-Inspired Uridine Containing LibraryCheng W.-C; Liu W.-J; Hu K.-H; Tan Y.-L; Lin Y.-T; Chen W.-A; Lo L.-C.; LEE-CHIANG LO ACS Combinatorial Science11
62016Development of a bifunctional andrographolide-based chemical probe for pharmacological studyHsu, Y.-H.; Hsu, Y.-L.; Liu, S.-H.; Liao, H.-C.; Lee, P.-X.; Lin, C.-H.; Lo, L.-C. ; Fu, S.-L.PLoS ONE118
72015Development of Activity-Based Probes for Imaging Human α- L -Fucosidases in CellsHsu, Y.-L.; N; akumar, M.; Lai, H.-Y.; Chou, T.-C.; Chu, C.-Y.; Lin, C.-H.; Lo, L.-C.; LEE-CHIANG LO Journal of Organic Chemistry1918
82015Detection of Human α- L -Fucosidases by a Quinone Methide-Generating Probe: Enhanced Activities in Response to Helicobacter pylori InfectionN; akumar, M.; Hsu, Y.-L.; Lin, J.C.-Y.; Lo, C.; Lo, L.-C.; Lin, C.-H.; LEE-CHIANG LO ChemBioChem1111
92014A convenient preparation of bis(4-methoxyphenyl)methanethiol and its application in the synthesis of biotin thioacidChou, T.-C.; Hsu, Y.-L.; Lo, L.-C.; LEE-CHIANG LO Journal of the Chinese Chemical Society00
102014Synthesis and evaluation of turn-on fluorescent probes for imaging steroid sulfatase activities in cellsTai, C.-H.; Lu, C.-P.; Wu, S.-H.; Lo, L.-C.; LEE-CHIANG LO Chemical Communications1717
112014Expedient carbonylation of aryl halides in aqueous or neat conditionAng, W.J.; Lo, L.-C.; Lam, Y.; LEE-CHIANG LO Tetrahedron2421
122014Synthesis of non-hydrolyzable substrate analogs for Asp-tRNAAsn/Glu-tRNAGln amidotransferaseKlinchan, C.; Hsu, Y.-L.; Lo, L.-C.; Pluempanupat, W.; Chuawong, P.; LEE-CHIANG LO Tetrahedron Letters45
132014Palladium-catalyzed annulation of internal alkynes in aqueous mediumAng, W.J.; Tai, C.-H.; Lo, L.-C.; Lam, Y.; LEE-CHIANG LO RSC Advances2931
142013Aconitamide, a novel alkaloid from the roots of Aconitum carmichaeliLee, T.-H.; Chen, Y.-C.; Lee, C.-K.; Chang, H.-S.; Kuo, C.-C.; Chao, C.-Y.; Lin, J.-J.; Lo, L.-C.; Kuo, Y.-H.; LEE-CHIANG LO Natural Product Communications65
152013Application of a recyclable fluorous oxime in the convenient synthesis of 3-amino-1,2-benzisoxazoles and 4-amino-1H-2,3-benzoxazinesAng, W.J.; Chu, C.-Y.; Chou, T.-C.; Lo, L.-C.; Lam, Y.; LEE-CHIANG LO Green Chemistry65
162013Diterpenoids with anti-inflammatory activity from the wood of cunninghamia konishiiChen, Y.-C.; Li, Y.-C.; You, B.-J.; Chang, W.-T.; Chao, L.K.; Lo, L.-C.; Wang, S.-Y.; Huang, G.-J.; Kuo, Y.-H.; LEE-CHIANG LO Molecules2020
172012Development of a fluorous, oxime-based palladacycle for microwave-promoted carbon-carbon coupling reactions in aqueous mediaSusanto, W.; Chu, C.-Y.; Ang, W.J.; Chou, T.-C.; Lo, L.-C.; Lam, Y.; LEE-CHIANG LO Green Chemistry5452
182012Fluorous oxime palladacycle: A precatalyst for carbon-carbon coupling reactions in aqueous and organic mediumSusanto, W.; Chu, C.-Y.; Ang, W.J.; Chou, T.-C.; Lo, L.-C.; Lam, Y.; LEE-CHIANG LO Journal of Organic Chemistry7673
192011Nitrophenylboronic acids as highly chemoselective probes to detect hydrogen peroxide in foods and agricultural productsLu, C.-P.; Lin, C.-T.; Chang, C.-M.; Wu, S.-H.; Lo, L.-C.; LEE-CHIANG LO Journal of Agricultural and Food Chemistry 6769
202007以化學蛋白質體學途徑來探討磷酸酯水解酵素(2/3)羅禮強 
212007芳香磺醯氟化物化學探針的開發及其在蛋白質體學上的應用　（新制多年期第1年）羅禮強 
222007芳香磺醯氟化物化學探針的開發及其在蛋白質體學上的應用　（新制多年期第2年）羅禮強 
232007以化學蛋白質體學途徑來探討磷酸酯水解酵素(1/3)羅禮強 
242007Development of an activity-based probe for steroid sulfatasesLu, C. P.; Ren, C. T.; Wu, S. H..; Chu, C. Y.; LEE-CHIANG LO ChemBioChem2726
252007Mutagenesis and mechanistic study of a glycoside hydrolase family 54 α-L-arabinofuranosidase from Trichoderma koningiiWan, C.-F.; Chen, W.-H.; Chen, C.-T.; Chang, M.D.-T.; Lo, L.-C.; Li, Y.-K.; LEE-CHIANG LO Biochemical Journal2017
262005Design of a Mechanism-Based Probe for Neuraminidase To Capture Influenza VirusesLu, Chun-Ping; Ren, Chien-Tai; Lai, Yi-Ning; Wu, Shih-Hsiung; Wang, Wei-Man; Chen, Jean-Yin; Lo, Lee-Chiang Angewandte Chemie3333
272005水解酵素活性標示之設計與合成及其應用於蛋白質體學與肝癌之研究（3/3）羅禮強 
282005Constitutive secretion of serum albumin requires reversible protein tyrosine phosphorylation events in trans-GolgiWebb, R.J.; Judah, J.D.; Lo, L.-C.; Thomas, G.M.H.; LEE-CHIANG LO American Journal of Physiology - Cell Physiology1515
292005以化學途徑來探討蛋白質水解酵素分佈之研究(1/2)羅禮強 
302005Study of the preferred modification sites of the quinone methide intermediate resulting from the latent trapping device of the activity probes for hydrolasesLo, Lee-Chiang; Chiang, Ying-Ling; Kuo, Chi-Hsien; Liao, Hsin-Kai; Chen, Yu-Ju; Lin, Jing-Jer; JING-JER LIN ; LEE-CHIANG LO Biochemical & Biophysical Research Communications3028
312004蛋白質水解酵素活性標示開發之研究(2/2)羅禮強 
322004Utilizing hydrolases of opposite enantiopreference for the preparation of both enantiomers of (1R,7aR)-(-)- and (1S,7aS)-(+)-3,6,7,7a-tetrahydro-1-hydroxy-7a-methyl-1H-inden-5(2H)-oneLo, Lee-Chiang ; Chou, Tzyy-Chao; Shie, Jung-JingChirality00
332004水解酵素活性標示之設計與合成及其應用於蛋白質體學與肝癌之研究（2/3）羅禮強 
342003Development of highly selective and sensitive probes for hydrogen peroxideLo, Lee-Chiang; Chu, Chi-Yuan; LEE-CHIANG LO Chemical Communications174165
352003蛋白質水解酵素活性標示開發之研究(1/2)羅禮強 
362003水解酵素活性標示之設計與合成及其應用於蛋白質體學與肝癌之研究(Ⅰ)羅禮強 
372002A CD Exciton Chirality Method for Determination of the Absolute Configuration of threo-β-Aryl-β-hydroxy-α-amino Acid DerivativesLo, Lee-Chiang ; Yang, Chun-Tzu; Tsai, Charng-ShengJournal of Organic Chemistry87
382002Design and Synthesis of Activity Probes for GlycosidasesTsai, Charng-Sheng; Li, Yaw-Kuen; Lo, Lee-Chiang Organic Letters7969
392002A convenient chemoenzymatic synthesis of (4aS,5S)-(+)-4,4a,5,6,7,8-hexahydro-5-hydroxy-4a-methylnaphthalen-2(3H)-oneLo, L.-C.; Shie, J.-J.; Chou, T.-C.; LEE-CHIANG LO Journal of Organic Chemistry77
402002蛋白質酪胺酸磷酸酯水解酵素標示之研究羅禮強 
412002A Convenient Chemoenzymatic Synthesis of (4aS,5S)-(+)-4,4a,5,6,7,8-Hexahydro- 5-hydroxy-4a-methylnaphthalen-2(3H)-oneLo, Lee-Chiang ; Shie, Jung-Jing; Chou, Tzyy-ChaoJournal of Organic Chemistry 
422001養生延命端粒脢抑制劑之中草藥成分篩選及其結構鑑定之研究羅禮強 
432001CD exciton chirality method for determination of the absolute configuration of β-hydroxy-α-amino acid derivativesLo, L.-C.; Chen, J.-Y.; Yang, C.-T.; Gu, D.-S.; LEE-CHIANG LO Chirality109
442001生物催化劑之標示及其鰓篩選開發之研究羅禮強 
452001Polymer-Supported Benzotriazoles as Catalysts in the Synthesis of Tetrahydroquinolines by Condensation of Aldehydes with Aromatic AminesTalukdar, Sanjay; Chen, Rong-Jiunn; Chen, Chao-Tsen ; Lo, Lee-Chiang ; Fang, Jim-Min Journal of Combinatorial Chemistry2422
462000生物催化劑篩選開發之研究羅禮強 
471999Design and Synthesis of an Activity Probe for Protein Tyrosine PhosphatasesLEE-CHIANG LO Journal of the Chinese Chemical Society1716
481999磷酸酯類水解酵素抑制劑之設計及合成羅禮強 
491999Lipase-catalyzed acetylation of N-acetylneuraminic acid derivativeLo, L.-C.; Hsiao, K.-F.; Ueng, S.-H.; Wu, S.-H.; Lo, Lee-Chiang Bioorganic and Medicinal Chemistry Letters43
501998利用酵素/化學合成途徑來製備唾液酸及其衍生物羅禮強 
511997Nanogram-scale derivatization of hydroxy groups for highly sensitive HPLC/MS/CD detectionZhao, N.; Guo, J.-S.; Lo, L.-C.; Berova, N.; Nakanishi, K.; Haupert, G.T.; Warrack, M.; Tymiak, A.A.; LEE-CHIANG LO Chemical Communications84
521997Chemical selection for catalysis in combinatorial antibody librariesJ; a, K.D.; Lo, L.-C.; Lo, C.-H.L.; Sim, M.-M.; Wang, R.; Wong, C.-H.; Lerner, R.A.; LEE-CHIANG LO Science182172
531996A versatile mechanism based reaction probe for the direct selection of biocatalystsLo, L.-C.; Lo, C.-H.L.; Ja, K.D.; Kassel, D.B.; Raushel, F.M.; LEE-CHIANG LO Bioorganic and Medicinal Chemistry Letters2523
541996Search for an endogenous mammalian cardiotonic factorNakanishi, K.; Berova, N.; Lo, L.-C.; Zhao, N.; Ludens, J.H.; Tymiak, A.A.; Warrack, B.; Haupert Jr.; G.T.; LEE-CHIANG LO Advances in Experimental Medicine and Biology5
551995Antibody-catalyzed phosphate triester hydrolysisRosenblum, J.S.; Lo, L.-C.; Li, T.; J; a, K.D.; Lerner, R.A.; LEE-CHIANG LO Angewandte Chemie (International Edition in English)2924
561994Malonofungin: an antifungal aminomalonic acid from Phaeoramularia fusimaculans.Berova, N.; Breinholt, J.; Jensen, G.W.; Kjaer, A.; Lo, L.C.; Nakanishi, K.; Nielsen, R.I.; Olsen, C.E.; Pedersen, C.; Stidsen, C.E.; LEE-CHIANG LO Acta chemica Scandinavica1616
571993Physicochemical characterization of a ouabain isomer isolated from bovine hypothalamusTymiak, A.A.; LEE-CHIANG LOet al. Proceedings of the National Academy of Sciences of the United States of America222221
581993Circular dichroic studies of 2-amino-2-deoxy-galactopyranosides - conformations of the 2-(N-acetyl-p-bromobenzamido) groupLo, L.-C.; Berova, N.; Nakanishi, K.; Morales, E.Q.; V?zquez, J.T.; LEE-CHIANG LO Tetrahedron: Asymmetry1111
591993Oligosaccharide microscale analysis by circular dichroic spectroscopy: Reference spectra for chromophoric d-fructofuranoside derivativesIkemoto, N.; Lo, L.-C.; Kim, O.K.; Berova, N.; Nakanishi, K.; LEE-CHIANG LO Carbohydrate Research33
601992Ferric chloride, an anomerization catalyst for the preparation of alkyl α-glycopyranosidesIkemoto, N.; Kim, O.K.; Lo, L.-C.; Satyanarayana, V.; Chang, M.; Nakanishi, K.; LEE-CHIANG LO Tetrahedron Letters5349
611992Detection of subpicomole levels of compounds containing hydroxyl and amino groups with the fluorogenic reagent, 2-naphthoylimidazoleIkemoto, N.; Lo, L.-C.; Nakanishi, K.; LEE-CHIANG LO Angewandte Chemie - International Edition30
621992Determination of the absolute stereochemistry of nemadectins α2 and αLo, L.-C.; Berova, N.; Nakanishi, K.; Schlingmann, G.; Carter, G.T.; Borders, D.B.; LEE-CHIANG LO Journal of the American Chemical Society22
631990Side reaction in peptide synthesis. Formation of oxazolidone derivativesChen, S.-T.; Lo, L.-C.; Wu, S.-H.; Wang, K.-T.; LEE-CHIANG LO International Journal of Peptide and Protein Research4
641989Separation of diastereomers of protected dipeptides by normal-phase high-performance liquid chromatographyLo, L.-C.; Chen, S.-T.; Wu, S.-H.; Wang, K.-T.; LEE-CHIANG LO Journal of Chromatography A55
651989Manipulation of enzymatic regioselectivity by structural modification of substratesWu, S.-H.; Lo, L.-C.; Chen, S.-T.; Wang, K.-T.; LEE-CHIANG LO Journal of Organic Chemistry116
661986The thin-layer Chromatographic separation of enantiomeric dipeptidesWang, K.T.; Chen, S.T.; Lo, L.C.; LEE-CHIANG LO Fresenius' Zeitschrift für Analytische Chemie139