https://scholars.lib.ntu.edu.tw/handle/123456789/196857
Title: | Pregnancy Achieved by Intracytoplasmic Sperm Injection Using Cryopreserved Vasal-Epididymal Sperm from a Man with Spinal Cord Injury 男性脊髓損傷患者利用冷凍輸精管─副睪丸精子透過卵子細胞質內注射成功懷孕 (病例報告) |
Authors: | CHEN, SHEE-UAN SHIEH, JENG-YUNG WANG, YEN-HO CHANG, HONG-CHIANG HO, HONG-NERNG YANG, YU-SHIH 陳思原 謝正勇 王顏和 張宏江 何弘能 楊友仕 |
Issue Date: | 1998 | Journal Volume: | v.79 | Journal Issue: | n.2 | Start page/Pages: | 218-221 | Source: | ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION | Abstract: | Anejaculation and poor semen quality are two major causes of infertility in men with spinal cord injury (SCI). The poor motility of retrieved sperm usually has low fertilization potential and is thought to be unfavorable for cryopreservation. This report describes a pregnancy after intracytoplasmic sperm injection (ICSI) with cryopreserved vasal- epididymal sperm from a man with SCI and anejaculation . An attempt was made to obtain sperm through electroejaculation, but no motile sperm were found in two trials. Therefore, the subject underwent vasal aspiration. The retrieved sperm had a concentration of 26 x 10(6)/mL and a motility of 3%. ICSI was considered to be the best choice for the couple, but the wife did not become pregnant in the first cycle of treatment. A successful pregnancy was achieved by ICSI in the second cycle using frozen-thawed sperm, supernumerary in the previous cycle, with a density of 5 x 10(6)/mL and 1% motility. A set of healthy twins, one boy and one girl, were delivered via cesarean section at 36 weeks of gestation. Complementary to other assisted reproductive techniques, ICSI may provide men with SCI a greater opportunity to father children. The supernumerary sperm, regardless of quality, should be cryopreserved to avoid the necessity and risk of repeated assisted ejaculations and aspirations of the genital tract. |
URI: | http://ntur.lib.ntu.edu.tw//handle/246246/93846 |
Appears in Collections: | 醫學系 |
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