https://scholars.lib.ntu.edu.tw/handle/123456789/309303
Title: | Supratentorial cerebrospinal fluid production rate in healthy adults: Quantification with two-dimensional cine phase-contrast MR imaging with high temporal and spatial resolution | Authors: | Huang, T.-Y. Chung, H.-W. Chen, M.-Y. Giiang, L.-H. Chin, S.-C. Lee, C.-S. Chen, C.-Y. Liu, Y.-J. HSIAO-WEN CHUNG |
Keywords: | Cerebrospinal fluid, flow dynamics, 167.12144; Cerebrospinal fluid, MR, 167.12144; Magnetic resonance (MR), phase imaging, 163.12144 | Issue Date: | 2004 | Journal Volume: | 233 | Journal Issue: | 2 | Start page/Pages: | 603-608 | Source: | Radiology | Abstract: | A method for objectively determining supratentorial cerebrospinal fluid (CSF) production rate is described. The method employs cine phase-contrast magnetic resonance imaging with high temporal and spatial resolution at the level of the aqueduct of Sylvius. Automatic encircling of the aqueduct was accomplished by using a pulsatility-based segmentation approach. Results in 23 healthy adults (18 men, five women; age range, 21-39 years) yielded an average CSF production rate of 305 μL/min ± 145 (standard deviation); this rate is in good agreement with literature-reported values obtained with invasive ventriculolumbar perfusion measurements. Average operator imprecision was 23.1% if automatic segmentation was not used. The proposed method is potentially an effective means for measuring supratentorial CSF production rate in humans. ? RSNA, 2004. |
URI: | http://www.scopus.com/inward/record.url?eid=2-s2.0-7044269532&partnerID=MN8TOARS http://scholars.lib.ntu.edu.tw/handle/123456789/309303 |
DOI: | 10.1148/radiol.2332030884 | SDG/Keyword: | accuracy; adult; article; brain aqueduct; cerebrospinal fluid; controlled study; female; human; imaging system; male; normal human; nuclear magnetic resonance; priority journal; quantitative analysis; Adult; Cerebral Aqueduct; Cerebrospinal Fluid; Humans; Magnetic Resonance Imaging, Cine; Male |
Appears in Collections: | 生醫電子與資訊學研究所 |
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