https://scholars.lib.ntu.edu.tw/handle/123456789/324556
標題: | Assessing the human health risks from exposure of inorganic arsenic through oyster (Crassostrea gigas) consumption in Taiwan | 作者: | CHEN-WUING LIU Liang, C.-P. Huang, F.M. Hsueh, Y.-M. |
關鍵字: | Health risk assessment; Inorganic arsenic; Oyster | 公開日期: | 2006 | 卷: | 361 | 期: | 1-3 | 起(迄)頁: | 57-66 | 來源出版物: | Science of the Total Environment | 摘要: | This study estimated the human health risk associated with ingesting inorganic arsenic through consumption of farmed oysters in Taiwan. Two hundred fifty-four samples of oyster (Crassostrea gigas) were collected from four townships in southwest coastal areas, where 90% of Taiwan's oysters are produced. The concentrations of total arsenic and arsenic species including As(V), As(III), monomethylarsonic acid (MMA) and dimethylarsinic acid (DMA) were analyzed. The analytical results reveal that the ratio of mean concentration among the four townships of inorganic As to total concentration of As in oysters is approximately 1.64%. The mean concentrations of As(III) and As(V) in oysters from the four townships range from 0.071 to 0.145 μg/g, and 0.032 to 0.062 μg/g respectively. The estimated target cancer risks (TR), based on a 95% occurrence probability from ingesting inorganic As by consuming oysters at a rate of 18.6-56 g/day, range from 1.26 × 10- 5 to 3.82 × 10- 5. The probabilities of TR fell within the range 10- 6-10- 4, suggesting that inorganic As uptake from farmed oysters is associated with a potential cancer risk. Moreover, a target hazard quotient (THQ) was used to evaluate the non-carcinogenic risk associated with ingesting inorganic As through oyster consumption at a rate of 18.6-56 g/day. The THQ values based on a 95% probability of exposure range from 0.071 to 0.214. All THQ values are below unity, indicating that farmed oyster consumption contributes only a little to the non-carcinogenic risk. Based on the estimation of the TR model, an ingestion rate of 1.6 g/day is recommended to meet the 95th percentile of carcinogenic risk, 10- 6, for exposure to inorganic As through the consumption of oysters in Taiwan. © 2005 Elsevier B.V. All rights reserved. |
URI: | http://www.scopus.com/inward/record.url?eid=2-s2.0-33646263822&partnerID=MN8TOARS http://scholars.lib.ntu.edu.tw/handle/123456789/324556 |
DOI: | 10.1016/j.scitotenv.2005.06.005 | SDG/關鍵字: | Arsenic; Biodiversity; Coastal zones; Concentration (process); Food preservation; Marine biology; Tumors; Dimethylarsinic acid (DMA); Health risk assessment; Inorganic arsenic; Oysters; Health risks; arsenic; cacodylic acid; carcinogen; inorganic compound; methanearsonic acid; arsenic; health care; inorganic compound; oyster culture; risk assessment; analytic method; article; cancer risk; concentration (parameters); crassostrea gigas; environmental exposure; food intake; health hazard; nonhuman; oyster; priority journal; probability; risk assessment; Taiwan; Animals; Arsenic; Arsenicals; Cacodylic Acid; Crassostrea; Environmental Exposure; Food Contamination; Humans; Risk Assessment; Seafood; Taiwan; Water Pollutants, Chemical; Asia; Eurasia; Far East; Taiwan; Crassostrea gigas; Ostreidae |
顯示於: | 生物環境系統工程學系 |
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