https://scholars.lib.ntu.edu.tw/handle/123456789/358173
標題: | T2-enhanced tensor diffusion trace-weighted image in the detection of hyper-acute cerebral infarction: Comparison with isotropic diffusion-weighted image | 作者: | Chou, M.-C. Tzeng, W.-S. Chung, H.-W. Wang, C.-Y. Liu, H.-S. Juan, C.-J. Lo, C.-P. Hsueh, C.-J. Chen, C.-Y. HSIAO-WEN CHUNG |
關鍵字: | Acute cerebral infarction; Tensor diffusion trace-weighted imaging | 公開日期: | 2010 | 卷: | 74 | 期: | 3 | 來源出版物: | European Journal of Radiology | 摘要: | Background and purpose: Although isotropic diffusion-weighted imaging (isoDWI) is very sensitive to the detection of acute ischemic stroke, it may occasionally show diffusion negative result in hyper-acute stroke. We hypothesize that high diffusion contrast diffusion trace-weighted image with enhanced T2 may improve stroke lesion conspicuity. Methods: Five hyper acute stroke patients (M:F = 0:5, average age = 61.8 ± 20.5 y/o) and 16 acute stroke patients (M:F = 11:5, average age = 67.7 ± 12 y/o) were examined six-direction tensor DWIs at b = 707 s/mm2. Three different diffusion-weighted images, including isotropic (isoDWI), diffusion trace-weighted image (trDWI) and T2-enhanced diffusion trace-weighted image (T2E_trDWI), were generated. Normalized lesion-to-normal ratio (nLNR) and contrast-to-noise ratio (CNR) of three diffusion images were calculated from each patient and statistically compared. Results: The trDWI shows better nLNR than isoDWI on both hyper-acute and acute stroke lesions, whereas no significant improvement in CNR. Nevertheless, the T2E_trDWI has statistically superior CNR and nLNR than those of isoDWI and trDWI in both hyper-acute and acute stroke. Conclusions: We concluded that tensor diffusion trace-weighted image with T2 enhancement is more sensitive to stroke lesion detection, and can provide higher lesion conspicuity than the conventional isotropic DWI for early stroke lesion delineation without the need of high-b-value technique. ? 2009 Elsevier Ireland Ltd. All rights reserved. |
URI: | http://www.scopus.com/inward/record.url?eid=2-s2.0-77952881987&partnerID=MN8TOARS http://scholars.lib.ntu.edu.tw/handle/123456789/358173 |
DOI: | 10.1016/j.ejrad.2009.04.023 | SDG/關鍵字: | Acute cerebral infarction; Acute ischemic stroke; Acute stroke; B value; Cerebral infarction; Conspicuity; Contrast to noise ratio; Diffusion weighted images; Enhanced diffusion; Isotropic diffusion; Stroke lesions; Tensors; Diffusion; adult; aged; article; brain infarction; clinical article; controlled study; diagnostic accuracy; diffusion weighted imaging; disease severity; female; human; image analysis; image quality; intermethod comparison; isotropic diffusion weighted imaging; male; priority journal; sensitivity and specificity; signal noise ratio; tensor diffusion trace weighted imaging; Acute Disease; Aged; Aged, 80 and over; Algorithms; Anisotropy; Brain; Cerebral Infarction; Diffusion Magnetic Resonance Imaging; Female; Humans; Image Enhancement; Image Interpretation, Computer-Assisted; Male; Middle Aged; Reproducibility of Results; Sensitivity and Specificity; Stroke |
顯示於: | 生醫電子與資訊學研究所 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。