https://scholars.lib.ntu.edu.tw/handle/123456789/358414
標題: | Spatiotemporal trends in oral cancer mortality and potential risks associated with heavy metal content in Taiwan soil | 作者: | Chiang, C.-T. Lian, I.-B. Su, C.-C. Tsai, K.-Y. YU-PIN LIN TSUN-KUO CHANG |
關鍵字: | Factor analysis; Heavy metal; Oral cancer; Soil pollution; Spatial autocorrelation; Spatial regression; Spatiotemporal | 公開日期: | 2010 | 卷: | 7 | 期: | 11 | 起(迄)頁: | 3916-3928 | 來源出版物: | International Journal of Environmental Research and Public Health | 摘要: | Central and Eastern Taiwan have alarmingly high oral cancer (OC) mortality rates, however, the effect of lifestyle factors such as betel chewing cannot fully explain the observed high-risk. Elevated concentrations of heavy metals in the soil reflect somewhat the levels of exposure to the human body, which may promote cancer development in local residents. This study assesses the space-time distribution of OC mortality in Taiwan, and its association with prime factors leading to soil heavy metal content. The current research obtained OC mortality data from the Atlas of Cancer Mortality in Taiwan, 1972-2001, and derived soil heavy metals content data from a nationwide survey carried out by ROCEPA in 1985. The exploratory data analyses showed that OC mortality rates in both genders had high spatial autocorrelation (Moran's I = 0.6716 and 0.6318 for males and females). Factor analyses revealed three common factors (CFs) representing the major pattern of soil pollution in Taiwan. The results for Spatial Lag Models (SLM) showed that CF1 (Cr, Cu, Ni, and Zn) was most spatially related to male OC mortality which implicates that some metals in CF1 might play as promoters in OC etiology. |
URI: | http://www.scopus.com/inward/record.url?eid=2-s2.0-78649755598&partnerID=MN8TOARS http://scholars.lib.ntu.edu.tw/handle/123456789/358414 |
DOI: | 10.3390/ijerph7113916 | SDG/關鍵字: | chromium; copper; heavy metal; nickel; zinc; article; cancer mortality; cancer risk; chemical industry; concentration (parameters); environmental exposure; factorial analysis; geographic distribution; human; mouth cancer; regression analysis; risk assessment; risk factor; sex difference; soil pollution; Taiwan; Piper betel |
顯示於: | 生物環境系統工程學系 |
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