https://scholars.lib.ntu.edu.tw/handle/123456789/399506
標題: | Anti-cancer efficacy of dietary polyphenols is mediated through epigenetic modifications | 作者: | Wu, J.-C. Lai, C.-S. Lee, P.-S. Ho, C.-T. Liou, W.-S. Wang, Y.-J. MIN-HSIUNG PAN |
公開日期: | 2016 | 卷: | 8 | 起(迄)頁: | 1-7 | 來源出版物: | Current Opinion in Food Science | 摘要: | Accumulating studies in tumorigenesis indicate that dysregulated gene expression caused by genetic and epigenetic changes lead to the formation of human cancers, and most dysregulated or dysfunctional genes are associated with cell proliferation, programmed cell death (PCD), metastasis, and, in part, tumor suppressor genes (TSGs) or oncogenes. Epigenetic modifications are important regulatory mechanisms that are induced by chemical treatment or environmental changes. Recently, studies have considered the effects of epigenetic modifications on tumorigenesis and disease. Over the past few decades, dietary polyphenols have become a focus of investigation because of their bioactive function in cancer prevention and treatment. In this review article, we summarize the current research on the anti-cancer effects of polyphenols and provide useful information to help promote polyphenol application in cancer research. ? 2016 Elsevier Ltd. |
URI: | http://www.scopus.com/inward/record.url?eid=2-s2.0-84957886168&partnerID=MN8TOARS http://scholars.lib.ntu.edu.tw/handle/123456789/399506 |
DOI: | 10.1016/j.cofs.2016.01.009 |
顯示於: | 食品科技研究所 |
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