https://scholars.lib.ntu.edu.tw/handle/123456789/413296
標題: | New and bioactive sesquiterpenes from Schisandra sphenanthera | 作者: | Mendbayar K. Lo I.-W. Liaw C.-C. Lin Y.-C. Fazary A.E. Kuo Y.-C. Wang H.-J. Chiang B.H. Liou S.-S. Shen Y.-C. |
關鍵字: | (-)-£^-Cuparenol;Immuno-modulating activity;Schisandra sphenanthera;Schisansphenins A and B | 公開日期: | 2011 | 卷: | 94 | 期: | 12 | 起(迄)頁: | 2295-2302 | 來源出版物: | Helvetica Chimica Acta | 摘要: | Three new sesquiterpenes, schisansphenins A (1) and B (2) and (-)-£^-cuparenol (3), were isolated from an acetone extract of the fruits of Schisandra sphenanthera. The known compound 4 was isolated for the frist time from a natural source. The structures of the isolated compounds were elucidated through extensive spectroscopic analyses, particularly 2D-NMR experiments ( 1H, 1H-COSY, HMQC, HMBC, and NOESY). A plausible biogenetic pathway for schisansphenin B (2) is proposed. Compounds 2 and 3 significantly reduced activation of NF-AT and NF-£eB in the luciferase-reporter assay. Copyright ? 2011 Verlag Helvetica Chimica Acta AG, Z?rich, Switzerland. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/413296 | ISSN: | 0018019X | DOI: | 10.1002/hlca.201100205 |
顯示於: | 食品科技研究所 |
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