https://scholars.lib.ntu.edu.tw/handle/123456789/413799
Title: | High-resolution optical coherence tomography with fiber induced broadband source and process algorithm for oral cancer study | Authors: | Hsu I.-J. Lu C.-W. CHIH-CHUNG YANG Chiang J.-P. CHII-WANN LIN |
Issue Date: | 2002 | Journal Volume: | 4619 | Start page/Pages: | 95-97 | Source: | Proceedings of SPIE - The International Society for Optical Engineering | Abstract: | A polarization controllable optical coherence tomography (OCT) system was built with the broadband source generated with femtosecond Ti:sapphire laser pulses in an ordinary fiber and a photonic crystal fiber. Spectral broadening in such fiber originated from self-phase modulation, four-wave mixing, Raman scattering, and other nonlinear-optics effects. Two different mode-locked Ti:sapphire lasers with 100 fsec and 12 fsec pulses were used. The generated spectral shape and width were compared in terms of the application to the OCT system. The relationship between the OCT resolution and the source spectrum shape was studied. Also, an algorithm was built for increasing the effective longitudinal resolution in data processing. The scheme of this algorithm meant to separate the contribution of the central portion from those of the tails in the interference fringe envelope. By removing the tail contribution to the scanning results, the effective longitudinal resolution was improved. Such a procedure is particularly important when the light source spectrum is not a well-defined shape. This procedure involved in the computation of a matrix inversion. The OCT system and the process algorithm were used for oral cancer study. Features of oral cancer were well identified. A probe was also fabricated for in vivo scan of oral tissues. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0036400183&doi=10.1117%2f12.470467&partnerID=40&md5=7facec5e9bee9972534fb5142ac56e18 https://scholars.lib.ntu.edu.tw/handle/123456789/413799 |
ISSN: | 0277786X | DOI: | 10.1117/12.470467 | SDG/Keyword: | Algorithms; Coherent light; Data processing; Fiber optics; Four wave mixing; Laser pulses; Light polarization; Light sources; Matrix algebra; Photons; Scanning; Self phase modulation; Spectrum analysis; Tumors; Optical coherence tomography; Tomography |
Appears in Collections: | 醫學工程學研究所 |
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