https://scholars.lib.ntu.edu.tw/handle/123456789/417236
標題: | A nested case-control study on the association between helicobacter pylori infection and gastric cancer risk in a cohort of 9775 men in Taiwan | 作者: | Lin J.-T. Wang L.-Y. Wang, Jin-Town Wang T.-H. Yang C.-S. Chen C.-J. |
關鍵字: | Gastric cancer; Helicobacter pylori; Nested case-control study | 公開日期: | 1995 | 卷: | 15 | 期: | 2 | 起(迄)頁: | 603-606 | 來源出版物: | Anticancer Research | 摘要: | A nested case-control study was carried out to investigate the association between Helicobacter pylori infection and gastric cancer risk in Taiwan. A total of 29 patients newly affected with gastric cancer and 220 healthy controls matched with cases on age, sex and residence were selected from a cohort of 9,775 men recruited from 1984 through 1986. Frozen serum samples collected at recruitment examination were tested for IgG antibodies against Helicobacter pylori by ant enzyme-linked immunosorbent assay. The average interval between serum collection and cancer diagnosis was 3.1 years. Gastric cancer cases had a higher seropositive prevalence (69%) than matched controls (59%) giving an odds ratio of 1.6 (95% confidence interval = 0.7-2.6). Compared with previous nested case-control studies. Helicobacter pylori infection in early childhood may be a risk factor for gastric cancer. However, a long induction period seems required for gastro-carcinogenesis associated with Helicobacter pylori infection. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0029052255&partnerID=40&md5=f4b9ddbdbddcc60d9dc275ca18c14294 https://scholars.lib.ntu.edu.tw/handle/123456789/417236 |
ISSN: | 0250-7005 | SDG/關鍵字: | immunoglobulin g antibody; adult; age; aged; article; blood sampling; cancer diagnosis; cancer risk; cohort analysis; controlled study; disease association; enzyme linked immunosorbent assay; gender; gram negative infection; helicobacter pylori; housing; human; major clinical study; male; prevalence; priority journal; risk factor; stomach cancer; stomach carcinogenesis; taiwan; Adult; Aged; Antibodies, Bacterial; Case-Control Studies; Child; Cocarcinogenesis; Cohort Studies; Comorbidity; Gastritis; Helicobacter Infections; Helicobacter pylori; Human; Immunoglobulin G; Male; Middle Age; Odds Ratio; Prevalence; Risk; Seroepidemiologic Studies; Stomach Neoplasms; Support, Non-U.S. Gov't; Taiwan; Time Factors |
顯示於: | 微生物學科所 |
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