https://scholars.lib.ntu.edu.tw/handle/123456789/461673
Title: | Placenta growth factor not vascular endothelial growth factor A or C can predict the early recurrence after radical resection of hepatocellular carcinoma | Authors: | MING-CHIH HO CHIUNG-NIEN CHEN HSIN-YU LEE FON-JOU HSIEH CHIA-TUNG SHUN Chang, Chi-Lun Lai, Yeun-Tyng PO-HUANG LEE |
Issue Date: | 2007 | Journal Volume: | 250 | Journal Issue: | 2 | Start page/Pages: | 237-249 | Source: | Cancer Letters | Abstract: | The purpose of this study was to evaluate the relationship between the expression of PlGF in tumor tissue and clinical outcomes in HCC patients. Tumor PlGF and vascular endothelial growth factor (VEGF)-A and VEGF-C mRNA were analyzed. Results demonstrated that patients with PlGF expression levels higher than median tended to have early recurrence compared to patients with PlGF expression lower than median (P = .031). In patients with AJCC stage II-III disease, this difference was even more significant (P = .002). In contrast, VEGF-A and VEGF-C could not predict early recurrence-free survival. Since PlGF expression correlated with early recurrence of HCC, PlGF may be an important prognostic indicator in HCC. ? 2006 Elsevier Ireland Ltd. All rights reserved. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-34047159945&doi=10.1016%2fj.canlet.2006.10.005&partnerID=40&md5=6ca5b2dc515350ee780671323b9d5651 https://scholars.lib.ntu.edu.tw/handle/123456789/461673 |
ISSN: | 0304-3835 | DOI: | 10.1016/j.canlet.2006.10.005 | SDG/Keyword: | messenger RNA; vasculotropin A; vasculotropin C; adult; aged; article; cancer recurrence; cancer staging; cancer survival; correlation analysis; evaluation; female; gene expression; human; human cell; human tissue; liver cell carcinoma; major clinical study; male; postoperative period; prediction; priority journal; prognosis; protein expression; Base Sequence; Carcinoma, Hepatocellular; DNA Primers; Humans; Liver Neoplasms; Pregnancy Proteins; Prognosis; Recurrence; Reverse Transcriptase Polymerase Chain Reaction; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor C |
Appears in Collections: | 醫學系 |
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