https://scholars.lib.ntu.edu.tw/handle/123456789/467538
標題: | Hydrogels based on schiff base linkages for biomedical applications | 作者: | Xu, J. Liu, Y. Hsu, S.-H. SHAN-HUI HSU |
關鍵字: | Click chemistry; Dynamic covalent bond; Hydrogel; Schiff base; Self-healing; Tissue engineering | 公開日期: | 2019 | 卷: | 24 | 期: | 16 | 來源出版物: | Molecules | 摘要: | Schiff base, an important family of reaction in click chemistry, has received significant attention in the formation of self-healing hydrogels in recent years. Schiff base reversibly reacts even in mild conditions, which allows hydrogels with self-healing ability to recover their structures and functions after damages. Moreover, pH-sensitivity of the Schiff base offers the hydrogels response to biologically relevant stimuli. Different types of Schiff base can provide the hydrogels with tunable mechanical properties and chemical stabilities. In this review, we summarized the design and preparation of hydrogels based on various types of Schiff base linkages, as well as the biomedical applications of hydrogels in drug delivery, tissue regeneration, wound healing, tissue adhesives, bioprinting, and biosensors. © 2019 by the authors. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/467538 | ISSN: | 14203049 | DOI: | 10.3390/molecules24163005 | SDG/關鍵字: | Schiff base; tissue adhesive; animal; chemistry; click chemistry; drug delivery system; drug effect; human; hydrogel; procedures; wound healing; Animals; Click Chemistry; Drug Delivery Systems; Humans; Hydrogels; Schiff Bases; Tissue Adhesives; Wound Healing |
顯示於: | 高分子科學與工程學研究所 |
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