https://scholars.lib.ntu.edu.tw/handle/123456789/496306
標題: | Impact of non-alcoholic fatty pancreas disease on glucose metabolism | 作者: | Yu T.-Y. CHIH-YUAN WANG |
關鍵字: | Diabetes mellitus; Metabolic syndrome; Non-alcoholic fatty pancreas disease | 公開日期: | 2017 | 出版社: | Blackwell Publishing | 卷: | 8 | 期: | 6 | 起(迄)頁: | 735-747 | 來源出版物: | Journal of Diabetes Investigation | 摘要: | With the increasing global epidemic of obesity, the clinical importance of non-alcoholic fatty pancreas disease (NAFPD) has grown. Even though the pancreas might be more susceptible to ectopic fat deposition compared with the liver, NAFPD is rarely discussed because of the limitation of detection techniques. In the past, NAFPD was considered as an innocent condition or just part of clinical manifestations during the course of obesity. Recently, a growing body of research suggests that NAFPD might be associated with β-cell dysfunction, insulin resistance and inflammation, which possibly lead to the development of diabetes and metabolic syndrome. The present review summarized the current literature on the epidemiology, potential pathophysiology, diagnostic techniques, impact of NAFPD on β-cell function and insulin resistance, and the clinical relevance of the interplay between NAFPD and glucometabolic disorders. ? 2017 The Authors. Journal of Diabetes Investigation published by Asian Association for the Study of Diabetes (AASD) and John Wiley & Sons Australia, Ltd |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85019841796&doi=10.1111%2fjdi.12665&partnerID=40&md5=bd22cac842c9f7b5da927317a1cc4734 https://scholars.lib.ntu.edu.tw/handle/123456789/496306 |
ISSN: | 2040-1116 | DOI: | 10.1111/jdi.12665 | SDG/關鍵字: | abdominal radiography; cell function; computer assisted tomography; diabetes mellitus; echography; endoscopic ultrasonography; glucose metabolism; human; insulin resistance; metabolic disorder; metabolic syndrome X; non alcoholic fatty pancreas disease; nonhuman; nuclear magnetic resonance imaging; nuclear magnetic resonance spectroscopy; pancreas disease; pancreas islet beta cell; pancreatic steatosis; pathophysiology; prevalence; priority journal; proton nuclear magnetic resonance; Review; steatosis; biological model; complication; metabolism; non insulin dependent diabetes mellitus; pancreas disease; pathology; physiology; glucose; Diabetes Mellitus, Type 2; Glucose; Humans; Insulin Resistance; Insulin-Secreting Cells; Models, Biological; Pancreatic Diseases |
顯示於: | 醫學系 |
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