https://scholars.lib.ntu.edu.tw/handle/123456789/510852
Title: | Acute coronary syndrome and suicide: A case-referent study | Authors: | Liu C.-H. Yeh M.-K. Wang J.-H. Weng S.-C. Bai M.-Y. JUNG-CHEN CHANG |
Keywords: | Acute coronary syndrome; Acute myocardial infarction; Suicide | Issue Date: | 2016 | Journal Volume: | 5 | Journal Issue: | 12 | Start page/Pages: | e003998 | Source: | Journal of the American Heart Association | Abstract: | Background--The high prevalence of acute coronary syndrome (ACS) represents a significant burden on healthcare resources. A robust association exists between depression and increased morbidity and mortality after ACS. This study examined the relationship between suicide and ACS after adjusting for depression and other comorbidities. Methods and Results--In this case-referent study conducted in Taiwan, the cases were people aged 35 years or older who died from suicide between 2000 and 2012 and 4 live referents, each matched by age, sex, and area of residence. The covariates adjusted for in the analysis were sociodemographic characteristics, physical comorbidities, and psychiatric disorders. We identified 41 050 persons who committed suicide and 164 200 referents. In the case and referent groups, 1027 (2.5%) and 2412 (1.5%) patients had ACS, respectively. After potential confounders were adjusted, ACS was significantly associated with increased odds of suicide (aOR=1.15, 95% confidence interval [CI]=1.05-1.26). The odds of suicide were highest during the initial 6 months post-ACS diagnosis (OR=3.05, 95% CI=2.55-3.65) and remained high for at least 4 years after ACS diagnosis. Conclusions--ACS patients are at an increased risk of suicide compared with otherwise healthy people. The risk of suicide is particularly high in the 6 months after ACS diagnosis. Our results suggest that we need to identify efficacious methods to recognize those at risk for suicide and to develop effective interventions to prevent such deaths. ? 2016 The Authors. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/510852 | ISSN: | 20479980 | DOI: | 10.1161/JAHA.116.003998 | SDG/Keyword: | acute coronary syndrome; adult; age; age distribution; aged; area of residence; Article; case referent study; clinical study; comorbidity; confidence interval; controlled study; disease association; dyslipidemia; female; gender; hospitalization; human; hypertension; ICD-9-CM; major clinical study; male; medical parameters; middle aged; morbidity; mortality; priority journal; risk assessment; risk factor; suicidal ideation; suicide; suicide attempt; acute coronary syndrome; case control study; demography; epidemiology; psychology; statistics and numerical data; suicide; Taiwan; Acute Coronary Syndrome; Adult; Aged; Case-Control Studies; Female; Humans; Male; Middle Aged; Residence Characteristics; Risk Factors; Suicide; Taiwan |
Appears in Collections: | 護理學系所 |
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