https://scholars.lib.ntu.edu.tw/handle/123456789/521719
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | WEN-CHUNG LEE | en_US |
dc.creator | Wen-Chung Lee | - |
dc.date.accessioned | 2020-11-19T08:19:03Z | - |
dc.date.available | 2020-11-19T08:19:03Z | - |
dc.date.issued | 2005 | - |
dc.identifier.issn | 1055-9965 | - |
dc.identifier.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-16444379528&doi=10.1158%2f1055-9965.EPI-04-0503&partnerID=40&md5=3843bf581d370facef03bb10da603af1 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/521719 | - |
dc.description.abstract | Genome-wide association scans for disease susceptibility genes of complex diseases require genotyping on a massive scale. A DNA pooling strategy for family-based association studies is described, which is robust to population stratification biases and to errors in pooling. It can achieve a statistical efficiency of 0.95 with ?1 of 8 or fewer genotyping efforts, and an efficiency of 0.90 with ?1 of 16 or fewer efforts compared with individual genotyping. The pooling method described in this article provides a tradeoff between genotyping efforts and subject recruitment efforts. Copyright ? 2005 American Association for Cancer Research. | - |
dc.language.iso | English | - |
dc.relation.ispartof | Cancer Epidemiology Biomarkers and Prevention | - |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | article; DNA determination; family; gene frequency; genetic association; genetic susceptibility; genome analysis; genotype; priority journal; statistical analysis; Alleles; DNA; Female; Gene Frequency; Gene Pool; Genetics, Population; Genotype; Humans; Male; Probability | - |
dc.title | A DNA pooling strategy for family-based association studies | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1158/1055-9965.EPI-04-0503 | - |
dc.identifier.pmid | 15824170 | - |
dc.identifier.scopus | 2-s2.0-16444379528 | - |
dc.relation.pages | 958-962 | - |
dc.relation.journalvolume | 14 | - |
dc.relation.journalissue | 4 | - |
item.fulltext | no fulltext | - |
item.cerifentitytype | Publications | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.grantfulltext | none | - |
item.openairetype | journal article | - |
item.languageiso639-1 | English | - |
crisitem.author.dept | Institute of Health Data Analytics and Statistics | - |
crisitem.author.dept | Public Health | - |
crisitem.author.orcid | 0000-0003-3171-7672 | - |
crisitem.author.parentorg | College of Public Health | - |
crisitem.author.parentorg | College of Public Health | - |
顯示於: | 流行病學與預防醫學研究所 |
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