https://scholars.lib.ntu.edu.tw/handle/123456789/522092| Title: | YC-1 induces lipid droplet formation in RAW 264.7 macrophages | Authors: | Tsui, Leo Chang, Shwu-Fen HSIANG-PO HUANG Fong, Tsorng-Harn Wang, I-Jong |
Keywords: | Macrophages; Foam cells; Oxidized low density lipoproteins; YC-1; cGMP-dependent protein kinase | Issue Date: | 15-Jan-2016 | Publisher: | BIOMED CENTRAL LTD | Journal Volume: | 23 | Journal Issue: | 1 | Source: | Journal of biomedical science | Abstract: | 3-(5'-Hydroxymethyl-2'-furyl)-1-benzylindazole (YC-1) is a potential anticancer drug that may activate soluble guanylyl cyclase (sGC) and increase the level of cyclic guanosine monophosphate (cGMP). The aim of this study was to explore the effects of YC-1 on lipid droplet accumulation and foam cell formation in macrophages. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/522092 | ISSN: | 1423-0127 | DOI: | 10.1186/s12929-016-0218-7 |
| Appears in Collections: | 基因體暨蛋白體醫學研究所 |
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