https://scholars.lib.ntu.edu.tw/handle/123456789/525003
標題: | Young children with behçet disease have more intestinal involvement | 作者: | Hung C.-H. JYH-HONG LEE Chen S.-T. YAO-HSU YANG YU-TSAN LIN LI-CHIEH WANG HSIN-HUI YU BOR-LUEN CHIANG |
公開日期: | 2013 | 卷: | 57 | 期: | 2 | 起(迄)頁: | 225-229 | 來源出版物: | Journal of Pediatric Gastroenterology and Nutrition | 摘要: | OBJECTIVE: Gastrointestinal (GI) involvement in childhood Beh?et disease (BD) is not well understood. We aimed to clarify the intestinal presentation in children with BD. METHODS: Medical records of 85 children with recurrent oral ulcers between 1990 and 2010 at the National Taiwan University Hospital were reviewed retrospectively. Twenty of them who fulfilled the Mason and Barnes criteria for the diagnosis of childhood BD were enrolled. The clinical and laboratory characteristics were analyzed. RESULTS: Among 20 patients, the median age at diagnosis was 13.2 years. The common presentations included oral ulcers (100%), genital ulcers (70%), skin lesions (65%), and GI symptoms (50%). Five of 10 patients with GI symptoms received endoscopic examinations and all had ulcers. Divided by the age of 10, patients younger than 10 years tended to have higher rates of GI symptoms initially and intestinal ulcers (P = 0.002 and 0.015, respectively). Platelet count was significantly lower in young patients (P = 0.0151). Patients without GI symptoms had higher rates of skin involvement than patients with GI symptoms (P = 0.019). CONCLUSIONS: Young children with BD tended to have more GI presentations. For children with BD younger than 10 years having GI symptoms, endoscopic examinations may be considered. Copyright ? 2013 by European Society for Pediatric Gastroenterology, Hepatology, and Nutrition and North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84880967556&doi=10.1097%2fMPG.0b013e3182936ec4&partnerID=40&md5=2fcc8be56238a5afd0d71abea35edced https://scholars.lib.ntu.edu.tw/handle/123456789/525003 |
ISSN: | 0277-2116 | DOI: | 10.1097/MPG.0b013e3182936ec4 | SDG/關鍵字: | adolescent; adult; article; Behcet disease; child; controlled study; female; gastrointestinal endoscopy; gastrointestinal symptom; genital ulcer; human; infant; intestine ulcer; major clinical study; male; mouth ulcer; outcome assessment; preschool child; priority journal; recurrent disease; retrospective study; school child; skin defect; thrombocyte count; Adolescent; Age Factors; Behcet Syndrome; Child; Child, Preschool; Endoscopy; Female; Gastrointestinal Diseases; Genitalia; Humans; Infant; Male; Mouth; Oral Ulcer; Platelet Count; Skin; Skin Diseases; Taiwan; Ulcer |
顯示於: | 醫學系 |
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