https://scholars.lib.ntu.edu.tw/handle/123456789/528571
標題: | Antimicrobial resistance of bacterial isolates from respiratory care wards in Taiwan: A horizontal surveillance study comparison of the characteristics of nosocomial infection and antimicrobial-resistant bacteria in adult Intensive Care Units and two respiratory care facilities for mechanically ventilated patients at a tertiary care centre in Taiwan | 作者: | Liu K.-S. Wang Y.-T. Lai Y.-C. Yu S.-F. Huang S.-J. Huang H.-J. Lu M.-C. PO-REN HSUEH |
公開日期: | 2011 | 卷: | 37 | 期: | 1 | 起(迄)頁: | 10-15 | 來源出版物: | International Journal of Antimicrobial Agents | 摘要: | The objectives of this study were to compare the incidence of nosocomial infections (NIs) and the distribution of resistant nosocomial pathogens in adult Intensive Care Units (ICUs) and two respiratory care facilities for prolonged mechanically ventilated patients [i.e. the respiratory care centre (RCC) and the respiratory care ward (RCW)] in a 1100-bed tertiary care hospital in Taiwan from 2003 to 2006. The overall incidences of NI for adult ICUs, the RCC and the RCW were 14.0, 10.3 and 5.0 per 1000 patient-days, respectively. Urinary tract infections, bloodstream infections and pneumonias occurred most frequently. The most common reported microorganisms in adult ICUs were non-fermentative Gram-negative bacilli (NFGNB) (33.0%), Enterobacteriaceae (26.5%), Candida spp. (18.2%), Staphylococcus aureus (8.9%), coagulase-negative staphylococci (CoNS) (4.9%) and enterococci (4.5%). In comparison, RCW patients had a higher proportion of NIs caused by S. aureus [odds ratio (OR) = 1.9], enterococci (OR = 2.2) and Enterobacteriaceae (OR = 2.2), but a lower proportion of CoNS (OR = 0.3), NFGNB (OR = 0.5) and Candida spp. (OR = 0.2). RCW patients had higher incidence rates of meticillin-resistant S. aureus (OR = 4.91) and extended-spectrum β-lactamase-producing Enterobacteriaceae (OR = 4.06) than ICU patients. Further study is needed to delineate the mechanisms responsible for the differences in resistance profile amongst pathogens associated with nosocomial infection in ICUs, RCCs and RCWs. ? 2010 Elsevier B.V. and the International Society of Chemotherapy. All rights reserved. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/528571 | ISSN: | 0924-8579 | DOI: | 10.1016/j.ijantimicag.2010.07.020 | SDG/關鍵字: | antibiotic agent; extended spectrum beta lactamase; adult; antibiotic resistance; artificial ventilation; bacterium identification; bacterium isolate; bloodstream infection; Candida; coagulase negative Staphylococcus; conference paper; controlled study; disease surveillance; Enterobacteriaceae; Enterococcus; Gram negative bacterium; hospital bed capacity; hospital infection; human; intensive care unit; length of stay; major clinical study; methicillin resistant Staphylococcus aureus; nonhuman; pneumonia; priority journal; respiratory care; species difference; Staphylococcus aureus; Taiwan; tertiary health care; urinary tract infection; Adult; Bacteremia; Bacteria; Bacterial Infections; Cross Infection; Drug Resistance, Bacterial; Humans; Incidence; Intensive Care Units; Microbial Sensitivity Tests; Mycoses; Pneumonia, Ventilator-Associated; Taiwan; Urinary Tract Infections |
顯示於: | 醫學院附設醫院 (臺大醫院) |
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