https://scholars.lib.ntu.edu.tw/handle/123456789/539383
標題: | Neonatal Behçet's disease without maternal history | 作者: | Chang Y.-S. YAO-HSU YANG BOR-LUEN CHIANG |
公開日期: | 2011 | 卷: | 30 | 期: | 12 | 起(迄)頁: | 1641-1645 | 來源出版物: | Clinical Rheumatology | 摘要: | A neonate presented with frequent vomiting since 10 days old, followed by severe diarrhea. Multiple oral ulcers and recurrent genital ulcers subsequently appeared. Colonoscopy showed multiple shallow round ulcerations in the colon. The symptoms responded well to a short course of oral prednisolone. There was a brief recurrence of vomiting, diarrhea, and oral ulcers at 2 months old. The mother has never had any symptoms of Beh?et's disease to date. This is the first reported case in literature of neonatal Beh?et's disease without a maternal history of Beh?et's disease, which raises doubts about the assumed role of maternal antibodies in the pathogenesis of neonatal Beh?et's disease. A literature review of neonatal Beh?et's disease shows that oral ulcers, skin lesions, fever, and leukocytosis are common features. However, only half of the patients fulfill the classical diagnostic criteria based on adult studies. A treatment consensus for neonatal cases is also lacking. ? 2011 Clinical Rheumatology. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-82655173893&doi=10.1007%2fs10067-011-1830-2&partnerID=40&md5=35c94a1ce46e71ca718d109ef07e4b5b https://scholars.lib.ntu.edu.tw/handle/123456789/539383 |
ISSN: | 0770-3198 | DOI: | 10.1007/s10067-011-1830-2 | SDG/關鍵字: | C reactive protein; prednisolone; Behcet disease; colonoscopy; diarrhea; erythrocyte sedimentation rate; female; fever; genital ulcer; human; leukocytosis; lymphocytic infiltration; mouth ulcer; neonatal weight loss; newborn; newborn disease; occult blood; priority journal; review; steroid therapy; vomiting; Adult; Behcet Syndrome; Female; Genital Diseases, Female; Humans; Infant, Newborn; Oral Ulcer; Prednisolone; Pregnancy; Recurrence |
顯示於: | 醫學系 |
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