https://scholars.lib.ntu.edu.tw/handle/123456789/539399
標題: | Clinical course and outcome of children with status asthmaticus treated in a pediatric intensive care unit: A 15-year review | 作者: | BOR-LUEN CHIANG Hsieh C.-T. LI-CHIEH WANG JYH-HONG LEE HSIN-HUI YU YU-TSAN LIN YAO-HSU YANG |
公開日期: | 2009 | 卷: | 42 | 期: | 6 | 起(迄)頁: | 488-493 | 來源出版物: | Journal of Microbiology, Immunology and Infection | 摘要: | Background and purpose: The purpose of this study was to analyze the clinical course and outcomes of children with status asthmaticus treated in a pediatric intensive care unit (PICU) in Taiwan. Methods: The medical charts of all patients aged from 2 to 18 years with status asthmaticus who were admitted to the PICU National Taiwan University Hospital, Taipei, Taiwan, from 1990 to 2006 were reviewed retrospectively. Results: Twenty eight children were admitted on 33 occasions; 4 patients had more than 1 admission. The mean age was 6.23 years (range, 2-17 years). No control medication was regularly used prior to admission for 81.8% of the episodes. The mean PICU stay was 2.55 days (range, 1-13 days) and, for 78.8% of episodes, the patients were discharged from the ICU within 2 days. For 11 episodes (33.3%), the patients required mechanical ventilation for a mean duration of 3.6 days. The mortality rate was 3.3% (n = 1). Complications included bronchopneumonia (57.6%), hemodynamic compromise (9.1%), neurologic symptoms (6.1%), and air leak (3.3%). Patients requiring mechanical ventilation had significantly lower initial pulse oximeter oxygen saturation (<90%), lower blood gas pH (<7.25), higher partial pressure of carbon dioxide, and longer duration of PICU and hospital stay (p < 0.05) when compared with patients not requiring mechanical ventilation. For patients with a history of repeated PICU admissions for asthma, the intubation rate was 77.7%. Conclusions: The prognosis for childhood status asthmaticus is favorable. The most common trigger factors were respiratory tract infection and poor asthma control. ? 2009 Journal of Microbiology, Immunology and Infection. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-77954674277&partnerID=40&md5=1294bdb1145ba4375d698dd23e0943f3 https://scholars.lib.ntu.edu.tw/handle/123456789/539399 |
ISSN: | 1684-1182 | SDG/關鍵字: | aminophylline; azithromycin; beta 2 adrenergic receptor stimulating agent; corticosteroid; ipratropium bromide; antiasthmatic agent; adolescent; article; artificial ventilation; asthmatic state; blood carbon dioxide tension; blood pH; bronchopneumonia; cardiovascular disease; child; clinical article; controlled study; disease course; female; hospitalization; human; intensive care unit; length of stay; male; medical record review; mortality; neurologic disease; oxygen saturation; preschool child; respiratory tract infection; retrospective study; school child; Taiwan; treatment outcome; age; asthmatic state; nonparametric test; recurrent disease; season; sex difference; statistics; Taiwan; Adolescent; Age Factors; Anti-Asthmatic Agents; Child; Child, Preschool; Female; Hospital Mortality; Humans; Intensive Care Units, Pediatric; Length of Stay; Male; Recurrence; Respiration, Artificial; Retrospective Studies; Seasons; Sex Factors; Statistics, Nonparametric; Status Asthmaticus; Taiwan; Treatment Outcome |
顯示於: | 醫學系 |
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