https://scholars.lib.ntu.edu.tw/handle/123456789/540745
標題: | Insulin resistance, obesity, and metabolic syndrome among non-diabetic pre- and post-menopausal women in North Taiwan | 作者: | Lin W.-Y. WEI-SHIUNG YANG Lee L.-T. Chen C.-Y. Liu C.-S. Lin C.-C. KUO-CHIN HUANG |
公開日期: | 2006 | 卷: | 30 | 期: | 6 | 起(迄)頁: | 912-917 | 來源出版物: | International Journal of Obesity | 摘要: | Objective: To investigate the relationship between the metabolic syndrome and its related factors among non-diabetic pre- and post-menopausal women in North Taiwan. Design: A cross-sectional study in a medical center in North Taiwan. Subjects: Five hundred and ninety-four, non-diabetic middle-aged women (age range=40-64 years, mean=48.9±5.4 years) were recruited. Measurements: The fasting plasma glucose, insulin, lipids levels and anthropometric indices were measured. The homeostasis model assessment was applied to estimate the degree of insulin resistance (HOMA-IR). Metabolic syndrome was defined by using the National Cholesterol Education Panel (NCEP) criteria and modified NCEP criteria (waist circumference >80 cm). Results: The prevalence of metabolic syndrome was 6.2% using NCEP criteria, and 8.9% using modified NCEP criteria. Post-menopausal women had a higher prevalence of metabolic syndrome and its individual components compared to pre-menopausal women except hyperglycemia and low HDL-C. In multiple logistic regression analysis with adjustment for age and menopausal status, both BMI and HOMA-IR were independently associated with the metabolic syndrome. Conclusion: The prevalence of metabolic syndrome was higher in post-menopausal than pre-menopausal women. Both obesity and insulin resistance may play an important role in the development of metabolic syndrome among the middle-aged women in North Taiwan. ? 2006 Nature Publishing Group All rights reserved. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-33744489576&doi=10.1038%2fsj.ijo.0803240&partnerID=40&md5=bf5fb2749cc22807503c554b6b09b75a https://scholars.lib.ntu.edu.tw/handle/123456789/540745 |
ISSN: | 0307-0565 | DOI: | 10.1038/sj.ijo.0803240 | SDG/關鍵字: | glucose; high density lipoprotein cholesterol; insulin; lipid; adult; anthropometry; article; controlled study; diabetes mellitus; female; glucose blood level; homeostasis; human; hyperglycemia; insulin blood level; insulin resistance; lipid blood level; major clinical study; menopause; metabolic syndrome X; multivariate logistic regression analysis; obesity; postmenopause; prevalence; priority journal; Taiwan; waist circumference; Adult; Anthropometry; Asian Continental Ancestry Group; Blood Glucose; Blood Pressure; Body Mass Index; Cross-Sectional Studies; Diabetes Complications; Female; Humans; Insulin; Insulin Resistance; Lipids; Metabolic Syndrome X; Middle Aged; Obesity; Postmenopause; Premenopause; Prevalence; Taiwan |
顯示於: | 醫學系 |
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