https://scholars.lib.ntu.edu.tw/handle/123456789/567277
標題: | Comorbidities of dry eye disease: A nationwide population-based study | 作者: | Wang T.-J. I-JONG WANG Hu C.-C. Lin H.-C. |
關鍵字: | autoimmune disorders; comorbidities; epidemiology; keratoconjunctivitis sicca | 公開日期: | 2012 | 卷: | 90 | 期: | 7 | 起(迄)頁: | 663-668 | 來源出版物: | Acta Ophthalmologica | 摘要: | Purpose: To investigate the comorbidities of dry eye disease in a nationwide population-based data in Taiwan. Methods: This study features a study group and a comparison group. The study group comprised 12 007 patients who sought ambulatory care for treatment of dry eye in 2005 and 2006. In total, 36 021 randomly selected patients were in the comparison group. Conditional logistic regression analyses conditioned on gender, age, monthly income and level of urbanization of the community in which the patient resided were conducted to calculate the odds ratio (OR) for each of 33 comorbidities among patients with and without dry eye disease. Results: The regression analyses revealed that compared to patients without dry eye disease, patients with dry eye disease were more likely to have comorbidities of ischaemic heart disease (OR = 1.36), hyperlipidaemia (OR = 1.68), cardiac arrhythmias (OR = 1.55), peripheral vascular disorders (OR = 1.57), stroke (OR = 1.31), migraines (OR = 1.76), myasthenia gravis (OR = 2.85), RA (OR = 2.86), systemic lupus erythematosus (OR = 3.98), asthma (OR = 1.25), pulmonary circulation disorders (OR = 1.37), diabetes with complications (OR = 1.31), hypothyroidism (OR = 1.94), liver diseases (OR = 1.71), peptic ulcers (OR = 1.76), hepatitis B (OR = 1.64), deficiency anaemias (OR = 1.31), depression (OR = 2.11), psychoses (OR = 1.87) and solid tumours without metastasis (OR = 1.41). Conclusions: This study demonstrates significantly higher prevalence of medical comorbidities in patients with dry eye disease in Taiwan. ? 2010 Acta Ophthalmol. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84868144644&doi=10.1111%2fj.1755-3768.2010.01993.x&partnerID=40&md5=685867ee934a2771c717a75f1fb3e544 https://scholars.lib.ntu.edu.tw/handle/123456789/567277 |
ISSN: | 1755-375X | DOI: | 10.1111/j.1755-3768.2010.01993.x | SDG/關鍵字: | adult; age; aged; ambulatory care; anemia; article; asthma; cerebrovascular accident; community; comorbidity; controlled study; depression; diabetes mellitus; dry eye; female; gender; heart arrhythmia; hepatitis B; human; hyperlipidemia; hypothyroidism; income; ischemic heart disease; liver disease; logistic regression analysis; lung disease; major clinical study; male; migraine; myasthenia gravis; peptic ulcer; peripheral vascular disease; population research; priority journal; psychosis; rheumatoid arthritis; solid tumor; systemic lupus erythematosus; Taiwan; urbanization; Adult; Aged; Comorbidity; Dry Eye Syndromes; Female; Humans; Male; Middle Aged; Odds Ratio; Population Surveillance; Prevalence; Risk Factors; Taiwan |
顯示於: | 醫學系 |
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