https://scholars.lib.ntu.edu.tw/handle/123456789/571523
標題: | Six lignans from Phyllanthus myrtifolius | 作者: | SHOEI-SHENG LEE Lin M.-T. Liu C.-L. Lin Y.-Y. Liu K.C.S.C. |
公開日期: | 1996 | 卷: | 59 | 期: | 11 | 起(迄)頁: | 1061-1065 | 來源出版物: | Journal of Natural Products | 摘要: | Six lignans comprising phyllamyricins D (1), E (2), and F (3) and phyllamyricosides A (4), B (5), and C (6) were isolated in a continuing study of Phyllanthus myrtifolius. Compounds 1 and 2 are 2a-methoxy-4-aryl-2,3- naphthalides. Compounds 3-6 belong to the 4-arylnaphthalene class, with compounds 4-6 being O-β-glucosides. Their structures were elucidated on the basis of spectral analysis. Compound 4 increased the activity of HIV-1 reverse transcriptase by 65% at a concentration of 1.89 μM. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0029954104&doi=10.1021%2fnp960322%2b&partnerID=40&md5=38f7edd2c1178160752e04393083624f https://scholars.lib.ntu.edu.tw/handle/123456789/571523 |
ISSN: | 1633864 | DOI: | 10.1021/np960322+ | SDG/關鍵字: | lignan derivative; phyllamyricin d; phyllamyricin e; phyllamyricin f; phyllamyricoside a; phyllamyricoside b; phyllamyricoside c; RNA directed DNA polymerase; unclassified drug; virus enzyme; article; controlled study; drug isolation; drug structure; enzyme activity; Human immunodeficiency virus 1; nonhuman; Phyllanthus; HIV-1 Reverse Transcriptase; Humans; Lignans; Magnetic Resonance Spectroscopy; Naphthalenes; Plants, Medicinal; Spectrometry, Mass, Fast Atom Bombardment; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Human immunodeficiency virus; Human immunodeficiency virus 1; Phyllanthus myrtifolius |
顯示於: | 藥學系 |
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