https://scholars.lib.ntu.edu.tw/handle/123456789/572735
標題: | Regulation of metE+ mRNA expression by FnrS small RNA in Salmonella enterica serovar Typhimurium | 作者: | Chien C.-W Chan Y.-F Shih P.-S Kuan J.-E Wu K.-F Wu C Wu W.-F. Shih, Po Shu WHEI-FEN WU Chien, Chia Wei Wu, Cindy Kuan, Jung En Chan, Yu Feng WHEI-FEN WU |
關鍵字: | Alkylation; Amino acids; Polymerase chain reaction; Proteins; Restoration; RNA; Transcription; FnrS; metE^+; Methionine; Non-coding RNAs; Salmonella enterica serovar Typhimurium; Salmonella; amino acid; bacterium; chemical binding; gene; gene expression; metabolism; methylation; protein; RNA; Salmonella enterica subsp. enterica serovar Typhimurium; bacterial protein; bacterial RNA; messenger RNA; methyltransferase; small untranslated RNA; base pairing; chemistry; conformation; enzymology; gene expression regulation; genetics; metabolism; nucleotide sequence; Salmonella enterica serovar Typhimurium; Bacterial Proteins; Base Pairing; Base Sequence; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Methyltransferases; Nucleic Acid Conformation; RNA, Bacterial; RNA, Messenger; RNA, Small Untranslated; Salmonella typhimurium | 公開日期: | 2019 | 卷: | 229 | 來源出版物: | Microbiological Research | 摘要: | Methionine is critical for variety of metabolic processes in biological organisms, acting as a precursor or intermediate for many final products. The last step for the synthesis of methionine is the methylation of homocysteine, which is catalyzed by MetE. Here, we use Salmonella enterica serovar Typhimurium LT2 to study the regulation of the metE+ gene by an anaerobically induced small non-coding RNA-FnrS, the expression of which is strictly dependent on the anaerobic regulator-FNR. The MetE-HA protein was expressed at an increased level in the fnrS- and hfq- deficient strains under anaerobic conditions. The Hfq protein is predicted to stabilize the binding between small RNA(s) and their target mRNA(s). A transcriptional (op) and translational (pr) metE |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85071500818&doi=10.1016%2fj.micres.2019.126319&partnerID=40&md5=3e08f7e104af61cbdcad4c934332822a https://scholars.lib.ntu.edu.tw/handle/123456789/572735 |
ISSN: | 9445013 | DOI: | 10.1016/j.micres.2019.126319 |
顯示於: | 農業化學系 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。