https://scholars.lib.ntu.edu.tw/handle/123456789/575852
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | Wang X | en_US |
dc.contributor.author | Guo J | en_US |
dc.contributor.author | Zhang Q | en_US |
dc.contributor.author | Zhu S | en_US |
dc.contributor.author | Liu L | en_US |
dc.contributor.author | Jiang X | en_US |
dc.contributor.author | Wei D.-H | en_US |
dc.contributor.author | Liu R.-S | en_US |
dc.contributor.author | Li L. | en_US |
dc.contributor.author | RU-SHI LIU | zz |
dc.creator | Wang X;Guo J;Zhang Q;Zhu S;Liu L;Jiang X;Wei D.-H;Liu R.-S;Li L. | - |
dc.date.accessioned | 2021-08-03T01:43:29Z | - |
dc.date.available | 2021-08-03T01:43:29Z | - |
dc.date.issued | 2020 | - |
dc.identifier.issn | 9574484 | - |
dc.identifier.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85077936690&doi=10.1088%2f1361-6528%2fab59eb&partnerID=40&md5=f15847fc115f674b7c04c1cb434038e6 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/575852 | - |
dc.description.abstract | Pathogenic bacterial infection, especially in the wound, may threaten human health. Developing new antibacterial materials for wound healing is still urgent. Metal nanoclusters have been explored as a novel antibacterial agent. Herein, biomolecule gelatin was chosen as a substrate and functionalized with gold/silver clusters for bacterial killing. Through a simple amidation reaction, gold/silver clusters were successfully conjugated in a gelatin substrate to obtain a Au/Ag@gelatin sponge. The presence of gold/silver clusters modified the porous structure of the gelatin. Thus, the water absorption and water retention of the Au/Ag@gelatin sponge were enhanced. More importantly, the gold/silver clusters show aggregation-enhanced emission and strong reactive oxygen generation, that endow the Au/Ag@gelatin sponge with a good antibacterial property. The good physical performance and favorable bactericidal activity of the Au/Ag@gelatin sponge suggest its potential for application as a wound dressing. ? 2020 IOP Publishing Ltd. | - |
dc.relation.ispartof | Nanotechnology | - |
dc.subject | Nanoclusters; Water absorption; antibacterial; Antibacterial materials; Antibacterial properties; Bacterial infections; Bactericidal activity; gelatin; Metal nanoclusters; Physical performance; Gold; antiinfective agent; gelatin; gold; metal nanoparticle; reactive oxygen metabolite; silver; animal; chemistry; drug effect; metabolism; microbial sensitivity test; pig; porosity; Pseudomonas aeruginosa; surface property; wound healing; Animals; Anti-Bacterial Agents; Gelatin; Gold; Metal Nanoparticles; Microbial Sensitivity Tests; Porosity; Pseudomonas aeruginosa; Reactive Oxygen Species; Silver; Surface Properties; Swine; Wound Healing | - |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | Nanoclusters; Water absorption; antibacterial; Antibacterial materials; Antibacterial properties; Bacterial infections; Bactericidal activity; gelatin; Metal nanoclusters; Physical performance; Gold; antiinfective agent; gelatin; gold; metal nanoparticle; reactive oxygen metabolite; silver; animal; chemistry; drug effect; metabolism; microbial sensitivity test; pig; porosity; Pseudomonas aeruginosa; surface property; wound healing; Animals; Anti-Bacterial Agents; Gelatin; Gold; Metal Nanoparticles; Microbial Sensitivity Tests; Porosity; Pseudomonas aeruginosa; Reactive Oxygen Species; Silver; Surface Properties; Swine; Wound Healing | - |
dc.title | Gelatin sponge functionalized with gold/silver clusters for antibacterial application | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1088/1361-6528/ab59eb | - |
dc.identifier.pmid | 31751976 | - |
dc.identifier.scopus | 2-s2.0-85077936690 | - |
dc.relation.journalvolume | 31 | - |
dc.relation.journalissue | 13 | - |
item.cerifentitytype | Publications | - |
item.fulltext | no fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.openairetype | journal article | - |
item.grantfulltext | none | - |
crisitem.author.dept | Chemistry | - |
crisitem.author.orcid | 0000-0002-1291-9052 | - |
crisitem.author.parentorg | College of Science | - |
顯示於: | 化學系 |
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