https://scholars.lib.ntu.edu.tw/handle/123456789/579859
Title: | Peri-radiosurgical administration of bevacizumab improves radiographic response to single and fractionated stereotactic radiosurgery for large brain metastasis | Authors: | Chen, Yi-Lun ABEL PO-HAO HUANG CHIA-CHUN WANG Chen, Hung-Yi YA-FANG CHEN FU-REN XIAO SHAO-LUN LU CHIA-HSIEN CHENG FENG-MING HSU |
Keywords: | Bevacizumab; Brain metastases; Radionecrosis; Response; Stereotactic radiosurgery | Issue Date: | Jul-2021 | Journal Volume: | 153 | Journal Issue: | 3 | Source: | Journal of neuro-oncology | Abstract: | Stereotactic radiosurgery (SRS) is a standard of care for brain metastases (BM) patients, yet large BM are at a greater risk for radionecrosis and local progression (LP). Concomitant bevacizumab and radiotherapy has been shown to improve outcomes in primary and metastatic brain tumors. This retrospective study investigated the efficacy and safety of concurrent bevacizumab and SRS for large BM. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/579859 | ISSN: | 0167594X | DOI: | 10.1007/s11060-021-03782-y | SDG/Keyword: | bevacizumab; bevacizumab; adult; Article; brain hemorrhage; brain metastasis; brain radiography; disease course; female; human; hypertension; local progression; major clinical study; male; multiple cycle treatment; perioperative period; radiation dose fra |
Appears in Collections: | 醫學系 |
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