https://scholars.lib.ntu.edu.tw/handle/123456789/611813
標題: | The response of hepatocyte cell volume to hyperthermia and its role in oedema | 作者: | O'Neill D.P. Peng T. Payne S.J. STEPHEN JOHN PAYNE |
關鍵字: | Cell volume;Diffusion Coefficients;Hepatocytes;Ion transports;Multiscale nature;New model;Varying temperature;Mathematical models;Cells;article;cell size;edema;fever;human;pathology;theoretical model;Cell Size;Edema;Fever;Humans;Models, Theoretical | 公開日期: | 2011 | 起(迄)頁: | 4305-4308 | 來源出版物: | Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS | 摘要: | A novel mathematical model for hepatocytes and surrounding volume is presented here; in addition to tracking ion transport and diffusion the new model allows for changing cell volume. Using temporally and spatially varying temperature as an input, this paper shows how differences between diffusion coefficients directly influence increases in cell volume. The multiscale nature of the model presents a possible link from established cellular equations to the observed clinical result of oedema present in thermal treatments of cancer. ? 2011 IEEE. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84055191155&doi=10.1109%2fIEMBS.2011.6091069&partnerID=40&md5=afa9228de4e46ec17f51593b5b6cbd0a https://scholars.lib.ntu.edu.tw/handle/123456789/611813 |
DOI: | 10.1109/IEMBS.2011.6091069 |
顯示於: | 應用力學研究所 |
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