https://scholars.lib.ntu.edu.tw/handle/123456789/625684
標題: | Cellular studies via dielectrophoresisbased cellular microarray chip | 作者: | Hsiung L.C Chiu C.L Yang C.H Wo A.M HSIN-YU LEE Jong D.S Chiu C.H Cheng J.Y Ho M.C Hsu C.Y Hsu M.C. |
關鍵字: | Celluar microarray; Concentration gradient; Dielectrophoresis | 公開日期: | 2007 | 起(迄)頁: | 1279-1281 | 來源出版物: | Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007 | 摘要: | This paper reports a dielectrophoresis (DEP)-based cellular microarray platform with embedded concentration gradient generator for cellular studies. Positive DEP was applied to pattern cells on collagen-coated substrate. Results show the approach requires fewer cells, compared to conventional approaches, to be patterned in microarray within minutes and with good uniformity. Further, the embedded concentration gradient generator provides concentrations with high repeatability. High cell viability is obtained after 24 hours incubation. The cellular microarray would allow batch testing with different drug/reagent concentrations in a single chip for high-throughput cellular studies. © 2007 CBMS. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85088680617&partnerID=40&md5=602cc7405accf458259e2aab8ec46f1b https://scholars.lib.ntu.edu.tw/handle/123456789/625684 |
SDG/關鍵字: | Cell viability; Cellular microarrays; Coated substrates; Concentration gradient generators; Conventional approach; High throughput; Positive DEP; Single chips; Electrophoresis |
顯示於: | 生命科學系 |
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