https://scholars.lib.ntu.edu.tw/handle/123456789/630831
標題: | Association of periodontitis and oral microbiomes with Alzheimer's disease: A narrative systematic review | 作者: | Mao, Samantha Huang, Chen-Pang Lan, Hsin Lau, Hing-Ger CHUN-PIN CHIANG YI-WEN CHEN |
關鍵字: | Alzheimer’s disease; Cognitive impairment; Oral microbiome; Periodontitis | 公開日期: | 十月-2022 | 出版社: | ELSEVIER TAIWAN | 卷: | 17 | 期: | 4 | 起(迄)頁: | 1762 | 來源出版物: | Journal of dental sciences | 摘要: | Alzheimer's disease (AD) is a neurodegenerative disorder and the most common form of dementia. The etiology for AD includes age, genetic susceptibility, neuropathology, and infection. Periodontitis is an infectious and inflammatory disease which mainly causes alveolar bone destruction and tooth loss. The evidence of a link between AD and periodontitis remains controversial. Thus far, studies reviewing the association between AD and periodontal disease have been insufficient from the viewpoint of the oral microbiome. The aim of this review was to focus on studies that have explored the relationship between the oral microbiome and AD development by using the next-generation sequencing technique. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/630831 | ISSN: | 1991-7902 | DOI: | 10.1016/j.jds.2022.07.001 |
顯示於: | 臨床牙醫學研究所 |
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