https://scholars.lib.ntu.edu.tw/handle/123456789/637990
Title: | TP53 status and impact on AML prognosis within the ELN 2022 risk classification | Authors: | Fleming, Shaun Tsai, Xavier Cheng-Hong Morris, Rhiannon HSIN-AN HOU Wei, Andrew H |
Issue Date: | 7-Dec-2023 | Journal Volume: | 142 | Journal Issue: | 23 | Start page/Pages: | 2029 | Source: | Blood | Abstract: | This study reports the following: (1) frequency of TP53 comutation within each component of the European LeukemiaNet 2022 acute myeloid leukemia risk classification, (2) relevance of TP53 mutated variant allelic fraction <10%, (3) prognostic impact of -7, -5/del(5q), -17/abn(17p), complex karyotype/monosomal karyotype, or myelodysplasia-related gene mutations with/without mutated TP53. |
URI: | https://pubmed.ncbi.nlm.nih.gov/37647854/ https://scholars.lib.ntu.edu.tw/handle/123456789/637990 |
ISSN: | 00064971 | DOI: | 10.1182/blood.2023020855 |
Appears in Collections: | 醫學系 |
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