https://scholars.lib.ntu.edu.tw/handle/123456789/638483
標題: | A novel mucosal bivalent vaccine of EV-A71/EV-D68 adjuvanted with polysaccharides from Ganoderma lucidum protects mice against EV-A71 and EV-D68 lethal challenge | 作者: | Lin, Yu-Li Cheng, Pei-Yun Chin, Chiao-Li Chuang, Kuan-Ting JING-YI LIN Chang, Ning Pan, Chun-Kei Lin, Cheng-Sheng Pan, Siao-Cian BOR-LUEN CHIANG |
關鍵字: | Acute flaccid myelitis; Acute flaccid paralysis; Adjuvant; Enterovirus A71; Enterovirus D68; Ganoderma lucidum polysaccharide; Intranasal; Mucosal vaccine | 公開日期: | 18-十二月-2023 | 卷: | 30 | 期: | 1 | 來源出版物: | Journal of biomedical science | 摘要: | Human enteroviruses A71 (EV-A71) and D68 (EV-D68) are the suspected causative agents of hand-foot-and-mouth disease, aseptic meningitis, encephalitis, acute flaccid myelitis, and acute flaccid paralysis in children. Until now, no cure nor mucosal vaccine existed for EV-A71 and EV-D68. Novel mucosal bivalent vaccines are highly important for preventing EV-A71 and EV-D68 infections. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/638483 | ISSN: | 1423-0127 | DOI: | 10.1186/s12929-023-00987-3 |
顯示於: | 臨床醫學研究所 |
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