https://scholars.lib.ntu.edu.tw/handle/123456789/639582
標題: | Circulating microRNAs in Sera Correlate with Soluble Biomarkers of Immune Activation but Do Not Predict Mortality in ART Treated Individuals with HIV-1 Infection: A Case Control Study | 作者: | Murray, Daniel D Suzuki, Kazuo Law, Matthew Trebicka, Jonel Neuhaus, Jacquie Wentworth, Deborah Johnson, Margaret Vjecha, Michael J Kelleher, Anthony D Emery, Sean JOHN TAYU LEE INSIGHT ESPRIT and SMART Study Groups |
公開日期: | 2015 | 卷: | 10 | 期: | 10 | 來源出版物: | PloS one | 摘要: | The use of anti-retroviral therapy (ART) has dramatically reduced HIV-1 associated morbidity and mortality. However, HIV-1 infected individuals have increased rates of morbidity and mortality compared to the non-HIV-1 infected population and this appears to be related to end-organ diseases collectively referred to as Serious Non-AIDS Events (SNAEs). Circulating miRNAs are reported as promising biomarkers for a number of human disease conditions including those that constitute SNAEs. Our study sought to investigate the potential of selected miRNAs in predicting mortality in HIV-1 infected ART treated individuals. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/639582 | ISSN: | 1932-6203 | DOI: | 10.1371/journal.pone.0139981 |
顯示於: | 健康政策與管理研究所 |
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