https://scholars.lib.ntu.edu.tw/handle/123456789/639614
標題: | A novel computer-assisted tool for 3D imaging of programmed death-ligand 1 expression in immunofluorescence-stained and optically cleared breast cancer specimens | 作者: | Lee, Yi-Hsuan Huang, Chung-Yen Hsieh, Yu-Han Yang, Chia-Hung Hung, Yu-Ling Chen, Yung-An Lin, Yu-Chieh Lin, Ching-Hung JIH-HSIANG LEE Wang, Ming-Yang Kuo, Wen-Hung Lin, Yen-Yin YEN-SHEN LU |
關鍵字: | Breast cancer; Immunofluorescence staining; Optical clearing; Programmed death-ligand 1; Three-dimensional imaging | 公開日期: | 24-一月-2024 | 卷: | 24 | 期: | 1 | 來源出版物: | BMC cancer | 摘要: | Programmed death-1 (PD-1) and programmed death-ligand 1 (PD-L1) are the two most common immune checkpoints targeted in triple-negative breast cancer (BC). Refining patient selection for immunotherapy is non-trivial and finding an appropriate digital pathology framework for spatial analysis of theranostic biomarkers for PD-1/PD-L1 inhibitors remains an unmet clinical need. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/639614 | ISSN: | 1471-2407 | DOI: | 10.1186/s12885-023-11748-8 |
顯示於: | 腫瘤醫學研究所 |
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