公開日期 | 標題 | 作者 | 來源出版物 | scopus | WOS | 全文 |
2002 | 2,3-Dimethoxybenzo[i]phenanthridines: Topoisomerase I-targeting anticancer agents | Li D.; Zhao B.; Sim S.-P.; TSAI-KUN LI ; Liu A.; Liu L.F.; LaVoie E.J. | Bioorganic and Medicinal Chemistry | 50 | 51 | |
2003 | 5H-Dibenzo[c,h]1,6-naphthyridin-6-ones: Novel topoisomerase I-targeting anticancer agents with potent cytotoxic activity | Ruchelman A.L.; Singh S.K.; Ray A.; Wu X.H.; Yang J.-M.; TSAI-KUN LI ; Liu A.; Liu L.F.; LaVoie E.J. | Bioorganic and Medicinal Chemistry | 111 | 109 | |
2003 | 8,9-Methylenedioxybenzo[i]phenanthridines: Topoisomerase I-targeting activity and cytotoxicity | Li D.; Zhao B.; Sim S.-P.; TSAI-KUN LI ; Liu A.; Liu L.F.; LaVoie E.J. | Bioorganic and Medicinal Chemistry | 40 | 41 | |
2003 | Acidic pH induces topoisomerase II-mediated DNA damage | Xiao H.; TSAI-KUN LI ; Yang J.-M.; Liu L.F. | Proceedings of the National Academy of Sciences of the United States of America | 68 | 54 | |
2022 | Activation of multiple proteolysis systems contributes to acute cadmium cytotoxicity | Yeh Y.-H.; Tsai C.-C.; Chen T.-W.; Lee C.-H.; Chang W.-J.; Hsieh M.-Y.; TSAI-KUN LI | Molecular and Cellular Biochemistry | 3 | 3 | |
1999 | Activation of topoisomerase II-mediated excision of chromosomal DNA loops during oxidative stress | TSAI-KUN LI ; Chen A.Y.; Yu C.; Mao Y.; Wang H.; Liu L.F. | Genes and Development | 150 | 139 | |
2003 | Aminoglycoside complexation with a DNA·RNA hybrid duplex: The thermodynamics of recognition and inhibition of RNA processing enzymes | Barbieri C.M.; TSAI-KUN LI ; Guo S.; Wang G.; Shallop A.J.; Pan W.; Yang G.; Gaffney B.L.; Jones R.A.; Pilch D.S. | Journal of the American Chemical Society | 31 | 28 | |
2012 | Anthracenedione-methionine conjugates are novel topoisomerase II-targeting anticancer agents with favorable drug resistance profiles | Lee C.-H.; Hsieh M.-Y.; LING-WEI HSIN ; Chen H.-C.; Lo S.-C.; Fan J.-R.; Chen W.-R.; Chen H.-W.; NEI-LI CHAN ; TSAI-KUN LI | Biochemical Pharmacology | 12 | 12 | |
2003 | Aza-analogs of dibenzo[c,h]cinnoline: Triazachrysenes as potent topoisomerase I-targeting anticancer agents | Singh S.K.; Ruchelman A.L.; Zhou N.; TSAI-KUN LI ; Liu A.; Liu L.F.; LaVoie E.J. | Medicinal Chemistry Research | 8 | | |
2011 | Calcium-induced cleavage of DNA topoisomerase I involves the cytoplasmic-nuclear shuttling of calpain 2 | Chou S.-M.; Huang T.-H.; Chen H.-C.; TSAI-KUN LI | Cellular and Molecular Life Sciences | 9 | 8 | |
2000 | The camptothecins: Unfolding their anticancer potential: Introduction | Liu L.F.; Desai S.D.; TSAI-KUN LI ; Yong M.A.O.; Sun M.E.I.; Sai-Peng S.I.M. | Annals of the New York Academy of Sciences | 1 | | |
2012 | Cell type-specific effects of Adenosine 5′-triphosphate and pyrophosphate on the antitumor activity of doxorubicin | Wang J.-S.; Chang Y.-L.; Yu Y.-H.; Chen C.-Y.; Kao M.-C.; TSAI-KUN LI ; WAN-WAN LIN | Cancer Science | 5 | 5 | |
2010 | Cellular processing determinants for the activation of damage signals in response to topoisomerase I-linked DNA breakage | Huang T.-H.; Chen H.-C.; Chou S.-M.; Yang Y.-C.; Fan J.-R.; TSAI-KUN LI | Cell Research | 13 | 12 | |
2008 | Cellular processing pathways contribute to the activation of etoposide-induced DNA damage responses | Fan J.-R.; Peng A.-L.; Chen H.-C.; Lo S.-C.; Huang T.-H.; TSAI-KUN LI | DNA Repair | 47 | 43 | |
1996 | Cellular resistance to topoisomerase poisons. | Rubin E.H.; TSAI-KUN LI ; Duann P.; Liu L.F. | Cancer treatment and research | 37 | 0 | |
2003 | Characterization of ARC-111 as a Novel Topoisomerase I-Targeting Anticancer Drug | TSAI-KUN LI ; Houghton P.J.; Desai S.D.; Daroui P.; Liu A.A.; Hars E.S.; Ruchelman A.L.; LaVoie E.J.; Liu L.F. | Cancer Research | 101 | 97 | |
2007 | Characterization of the uracil-DNA glycosylase activity of Epstein-Barr virus BKRF3 and its role in lytic viral DNA replication | Lu C.-C.; Huang H.-T.; Wang J.-T.; Slupphaug G.; TSAI-KUN LI ; Wu M.-C.; Chen Y.-C.; Lee C.-P.; MEI-RU CHEN | Journal of Virology | 30 | 29 | |
2020 | Design, synthesis, and biological evaluation of heterotetracyclic quinolinone derivatives as anticancer agents targeting topoisomerases | Lee, Jiann-Fong; Chang, Ting-Yu; Liu, Zheng-Fang; Lee, Nian-Zhe; Yeh, Yen-Hsiu; Chen, Yi-Song; Chen, Tsung-Chih; Chou, Hao-Syun; TSAI-KUN LI ; Lee, Sung-Bau; Lin, Mei-Hsiang | European Journal of Medicinal Chemistry | 10 | 9 | |
2002 | Diaza- and triazachrysenes: Potent topoisomerase-targeting agents with exceptional antitumor activity against the human tumor xenograft, MDA-MB-435 | Ruchelman A.L.; Singh S.K.; Wu X.; Ray A.; Yang J.-M.; TSAI-KUN LI ; Liu A.; Liu L.F.; LaVoie E.J. | Bioorganic and Medicinal Chemistry Letters | 56 | 56 | |
1997 | Differential poisoning of topoisomerases by menogaril and nogalamycin dictated by the minor groove-binding nogalose sugar | Sim S.-P.; Gatto B.; Yu C.; Liu A.A.; TSAI-KUN LI ; Pilch D.S.; LaVoie E.J.; Liu L.F. | Biochemistry | 39 | 36 | |