| 公開日期 | 標題 | 作者 | 來源出版物 | scopus | WOS | 全文 |
1 | 2008 | The activation gate and gating mechanism of the NMDA receptor | Chang H.-R.; Chung-Chin Kuo | Journal of Neuroscience | 80 | 76 | |
2 | 2019 | Anomalous enhancement of resurgent Na+ currents at high temperatures by SCN9A mutations underlies the episodic heat-enhanced pain in inherited erythromelalgia | Huang C.-W.; Lai H.-J.; Huang P.-Y.; MING-JEN LEE ; Chung-Chin Kuo | Scientific Reports | 4 | 13 | |
3 | 2021 | Anticonvulsant vs. Proconvulsant Effect of in situ Deep Brain Stimulation at the Epileptogenic Focus | Chou P.; CHUNG-CHIN KUO | Frontiers in Systems Neuroscience | 0 | 1 | |
4 | 2016 | The Biophysical Basis Underlying Gating Changes in the p.V1316A Mutant Nav1.7 Channel and the Molecular Pathogenesis of Inherited Erythromelalgia | Huang C.-W.; Lai H.-J.; Huang P.-Y.; MING-JEN LEE ; Chung-Chin Kuo | PLoS Biology | 10 | 6 | |
5 | 2004 | Block of tetrodotoxin-resistant Na+ channel pore by multivalent cations: Gating modification and Na+ flow dependence | Chung-Chin Kuo ; Chen Wan Yu; Yang Y.-C. | Journal of General Physiology | 31 | 28 | |
6 | 1993 | Block of the L-type Ca2+ channel pore by external and internal Mg2+ in rat phaeochromocytoma cells. | Chung-Chin Kuo ; Hess P. | The Journal of Physiology | 61 | 60 | |
7 | 2014 | The bundle crossing region is responsible for the inwardly rectifying internal spermine block of the Kir2.1 channel | Huang C.-W.; Chung-Chin Kuo | Pflugers Archiv European Journal of Physiology | 8 | 8 | |
8 | 1997 | Carbamazepine inhibition of neuronal Na+ currents: Quantitative distinction from phenytoin and possible therapeutic implications | Chung-Chin Kuo ; Chen R.-S.; LU LU ; Chen R.-C. | Molecular Pharmacology | 145 | 135 | |
9 | 1997 | Characterization of lamotrigine inhibition of Na+ channels in rat hippocampal neurones | Chung-Chin Kuo ; LU LU | British Journal of Pharmacology | 134 | 120 | |
10 | 2007 | Characterization of the gating conformational changes in the felbamate binding site in NMDA channels | Chang H.-R.; Chung-Chin Kuo | Biophysical Journal | 10 | 10 | |
11 | 1993 | Characterization of the high-affinity Ca2+ binding sites in the L-type Ca2+ channel pore in rat phaeochromocytoma cells. | Chung-Chin Kuo ; Hess P. | The Journal of Physiology | 89 | 83 | |
12 | 1998 | A common anticonvulsant binding site for phenytoin, carbamazepine, and lamotrigine in neuronal Na+ channels | Chung-Chin Kuo | Molecular Pharmacology | 190 | 163 | |
13 | 1997 | Deactivation retards recovery from inactivation in Shaker K+ channels | Chung-Chin Kuo | Journal of Neuroscience | 7 | 8 | |
14 | 2022 | Deep brain stimulation rectifies the noisy cortex and irresponsive subthalamus to improve parkinsonian locomotor activities | Lee, Lan-Hsin Nancy; Huang, Chen-Syuan; Wang, Ren-Wei; Lai, Hsing-Jung; Chung, Chih-Ching; Yang, Ya-Chin; CHUNG-CHIN KUO | NPJ Parkinson's disease | 1 | 1 | |
15 | 2020 | Delta-Frequency Augmentation and Synchronization in Seizure Discharges and Telencephalic Transmission | Chou P.; Wang G.-H.; Hsueh S.-W.; Yang Y.-C.; CHUNG-CHIN KUO | iScience | 9 | 8 | |
16 | 2014 | Deranged NMDAergic cortico-subthalamic transmission underlies parkinsonian motor deficits | MING-KAI PAN ; CHUN-HWEI TAI ; Liu, W.-C.; Pei, J.-C.; WEN-SUNG LAI ; CHUNG-CHIN KUO | Journal of Clinical Investigation | 27 | 26 | |
17 | 2020 | Desensitization of NMDA channels requires ligand binding to both GluN1 and GluN2 subunits to constrict the pore beside the activation gate | Chen Y.-S.; Tu Y.-C.; Lai Y.-C.; Liu E.; Yang Y.-C.; Chung-Chin Kuo | Journal of Neurochemistry | 3 | 1 | |
18 | 2015 | The differential contribution of GluN1 and GluN2 to the gating operation of the NMDA receptor channel | Tu Y.-C.; Chung-Chin Kuo | Pflugers Archiv European Journal of Physiology | 10 | 10 | |
19 | 2015 | Driving force-dependent block by internal Ba2+ on the Kir2.1 channel: Mechanistic insight into inward rectification | Hsieh C.-P.; Chung-Chin Kuo ; Huang C.-W. | Biophysical Chemistry | 6 | 6 | |
20 | 2024 | Dynamic electrical synapses rewire brain networks for persistent oscillations and epileptogenesis | Yang, Ya-Chin; Wang, Guan-Hsun; Chou, Ping; Hsueh, Shu-Wei; Lai, Yi-Chen; CHUNG-CHIN KUO | Proceedings of the National Academy of Sciences of the United States of America | | | |
21 | 2002 | Effect of Na+ flow on Cd2+ block of tetrodotoxin-resistant Na+ channels | Chung-Chin Kuo ; Lin T.-J.; Hsieh C.-P. | Journal of General Physiology | 16 | 15 | |
22 | 2009 | The external pore loop interacts with S6 and S3-S4 linker in domain 4 to assume an essential role in gating control and anticonvulsant action in the Na+ channel | Yang Y.-C.; Hsieh J.-Y.; Chung-Chin Kuo | Journal of General Physiology | 26 | 23 | |
23 | 2007 | Extracellular proton-modulated pore-blocking effect of the anticonvulsant felbamate on NMDA channels | Chang H.-R.; Chung-Chin Kuo | Biophysical Journal | 6 | 4 | |
24 | 2000 | Facilitation of recovery from inactivation by external NA+ and location of the activation gate in neuronal NA+ channels | Chung-Chin Kuo ; Liao S.-Y. | Journal of Neuroscience | 20 | 20 | |
25 | 2015 | Flow- and voltage-dependent blocking effect of ethosuximide on the inward rectifier K+ (Kir2.1) channel | Huang C.-W.; Chung-Chin Kuo | Pflugers Archiv European Journal of Physiology | 6 | 6 | |
26 | 2011 | Functional extension of amino acid triads from the fourth transmembrane segment (S4) into its external linker in Shaker K + channels | Yang Y.-C.; Lin S.; Chang P.-C.; Lin H.-C.; CHUNG-CHIN KUO | Journal of Biological Chemistry | 5 | 5 | |
27 | 1992 | A functional view of the entrances of L-type Ca2+ channels: estimates of the size and surface potential at the pore mouths | Chung-Chin Kuo ; Hess P. | Neuron | 30 | 34 | |
28 | 1993 | G-protein modulation of ion permeation through N-type calcium channels | Chung-Chin Kuo ; Bean B.P. | Nature | 60 | 68 | |
29 | 2014 | Gating of the Kir2.1 Channel at the Bundle Crossing Region by Intracellular Spermine and Other Cations | Huang C.-W.; Chung-Chin Kuo | Journal of Cellular Physiology | 4 | 4 | |
30 | 2022 | The genesis and functional consequences of cortico-subthalamic beta augmentation and excessive subthalamic burst discharges after dopaminergic deprivation | Lai, Hsing-Jung; Deng, Chuan-Rou; Wang, Ren-Wei; Lee, Lan-Hsin Nancy; CHUNG-CHIN KUO | Experimental neurology | 1 | 0 | |
31 | 2021 | Glutamate transmission rather than cellular pacemaking propels excitatory-inhibitory resonance for ictogenesis in amygdala | Wang G.-H.; Chou P.; Hsueh S.-W.; Yang Y.-C.; CHUNG-CHIN KUO | Neurobiology of Disease | 6 | 5 | |
32 | 2021 | How Can an Na+ Channel Inhibitor Ameliorate Seizures in Lennox–Gastaut Syndrome? | Lin Y.-C.; Lai Y.-C.; Chou P.; Hsueh S.-W.; Lin T.-H.; Huang C.-S.; Wang R.-W.; Yang Y.-C.; CHUNG-CHIN KUO | Annals of Neurology | 5 | 3 | |
33 | 2007 | A hydrophobic element secures S4 voltage sensor in position in resting Shaker K+ channels | Yang Y.-C.; Own C.-J.; Chung-Chin Kuo | Journal of Physiology | 11 | 10 | |
34 | 2020 | Hyperpolarization of the subthalamic nucleus alleviates hyperkinetic movement disorders | CHUN-HWEI TAI ; MING-KAI PAN ; SHENG-HONG TSENG ; Wang T.-R.; Chung-Chin Kuo | Scientific Reports | 7 | 7 | |
35 | 1998 | Imipramine inhibition of transient K+ current: An external open channel blocker preventing fast inactivation | Chung-Chin Kuo | Biophysical Journal | 30 | 31 | |
36 | 2005 | An inactivation stabilizer of the Na+ channel acts as an opportunistic pore blocker modulated by external Na+ | Yang Y.-C.; Chung-Chin Kuo | Journal of General Physiology | 21 | 19 | |
37 | 2002 | Inhibition of Na + current by imipramine and related compounds: Different binding kinetics as an inactivation stabilizer and as an open channel blocker | Yang Y.-C.; Chung-Chin Kuo | Molecular Pharmacology | 55 | 52 | |
38 | 2000 | Inhibition of Na+ current by diphenhydramine and other diphenyl compounds: Molecular determinants of selective binding to the inactivated channels | Chung-Chin Kuo ; Huang R.-C.; Lou B.-S. | Molecular Pharmacology | 81 | 78 | |
39 | 2020 | Inhibition of neuronal Na+ currents by lacosamide: Differential binding affinity and kinetics to different inactivated states | Peng Y.-S.; Wu H.-T.; Lai Y.-C.; Chen J.-L.; Yang Y.-C.; CHUNG-CHIN KUO | Neuropharmacology | 7 | 5 | |
40 | 2024 | Inhibition of resurgent Na+ currents by rufinamide | Chen, Jian-Lin; CHUNG-CHIN KUO | Neuropharmacology | | | |
41 | 1993 | Ion permeation through the L-type Ca2+ channel in rat phaeochromocytoma cells: two sets of ion binding sites in the pore. | Chung-Chin Kuo ; Hess P. | The Journal of Physiology | 98 | 99 | |
42 | 2010 | Ionic flow enhances low-affinity binding: a revised mechanistic view into Mg2+ block of NMDA receptors | Yang Y.-C.; Lee C.-H.; Chung-Chin Kuo | Journal of Physiology | 13 | 12 | |
43 | 1999 | K + binding sites and interactions between permeating K+ ions at the external pore mouth of an inward rectifier K+ channel (Kir2.1) | Shieh R.-C.; Chang J.-C.; Chung-Chin Kuo | Journal of Biological Chemistry | 17 | 16 | |
44 | 2010 | Lidocaine, carbamazepine, and imipramine have partially overlapping binding sites and additive inhibitory effect on neuronal Na+ channels | Yang Y.-C.; Huang C.-S.; Chung-Chin Kuo | Anesthesiology | 42 | 42 | |
45 | 2016 | Modulation of NMDA channel gating by Ca2+ and Cd2+ binding to the external pore mouth | Tu Y.-C.; Yang Y.-C.; Chung-Chin Kuo | Scientific Reports | 9 | 8 | |
46 | 2011 | Modulation of subthalamic T-type Ca2+ channels remedies locomotor deficits in a rat model of Parkinson disease | CHUN-HWEI TAI ; Yang Y.-C.; MING-KAI PAN ; Huang C.-S.; Chung-Chin Kuo | Journal of Clinical Investigation | 59 | 58 | |
47 | 2008 | Molecular determinants of the anticonvulsant felbamate binding site in the N-methyl-D-aspartate receptor | Chang H.-R.; Chung-Chin Kuo | Journal of Medicinal Chemistry | 21 | 13 | |
48 | 1994 | Na+ channels must deactivate to recover from inactivation | Chung-Chin Kuo ; Bean B.P. | Neuron | 259 | 253 | |
49 | 2016 | Neuronal firing patterns outweigh circuitry oscillations in parkinsonian motor control | MING-KAI PAN ; Kuo, S.-H.; CHUN-HWEI TAI ; Liou, J.-Y.; Pei, J.-C.; Chang, C.-Y.; Wang, Y.-M.; Liu, W.-C.; Wang, T.-R.; WEN-SUNG LAI ; CHUNG-CHIN KUO | Journal of Clinical Investigation | 30 | 28 | |
50 | 2003 | The position of the fourth segment of domain 4 determines status of the inactivation gate in Na+ channels | Yang Y.-C.; Chung-Chin Kuo | Journal of Neuroscience | 26 | 19 | |
51 | 1995 | Postnatal development of cortical acetylcholinesterase-rich neurons in the rat brain: Permanent and transient patterns | Geula C.; Mesulam M.-M.; Chung-Chin Kuo ; Tokuno H. | Experimental Neurology | 29 | 29 | |
52 | 2001 | Recovery from inactivation of T-type Ca2+ channels in rat thalamic neurons | Chung-Chin Kuo ; Yang S. | Journal of Neuroscience | 32 | 32 | |
53 | 2022 | Selective stabilization of the intermediate inactivated Na+ channel by the new-generation anticonvulsant rufinamide | Lin Y.-C.; Lai Y.-C.; Lin T.-H.; Yang Y.-C.; CHUNG-CHIN KUO | Biochemical Pharmacology | 1 | 1 | |
54 | 1994 | Slow binding of phenytoin to inactivated sodium channels in rat hippocampal neurons | Chung-Chin Kuo ; Bean B.P. | Molecular Pharmacology | 185 | 176 | |
55 | 2012 | Subthalamic discharges as a causal determinant of parkinsonian motor deficits | CHUN-HWEI TAI ; MING-KAI PAN ; Lin J.J.; Huang C.-S.; Yang Y.-C.; Chung-Chin Kuo | Annals of Neurology | 28 | 25 | |
56 | 2016 | A synergistic blocking effect of Mg2+ and spermine on the inward rectifier K+ (Kir2.1) channel pore | Huang C.-W.; Chung-Chin Kuo | Scientific Reports | 6 | 5 | |
57 | 2019 | Temperature dependence of the biophysical mechanisms underlying the inhibition and enhancement effect of amiodarone on hERG channelss | Lo Y.-C.; Chung-Chin Kuo | Molecular Pharmacology | 3 | 3 | |
58 | 2015 | The temporal profiles of changes in nerve excitability indices in familial amyloid polyneuropathy | Lai H.-J.; Chiang Y.-W.; Yang C.-C.; SUNG-TSANG HSIEH ; CHI-CHAO CHAO ; MING-JEN LEE ; Chung-Chin Kuo | PLoS ONE | 15 | 11 | |
59 | 2004 | Use-Dependent Inhibition of the N-Methyl-D-aspartate Currents by Felbamate: A Gating Modifier with Selective Binding to the Desensitized Channels | Chung-Chin Kuo ; Lin B.-J.; Chang H.-R.; Hsieh C.-P. | Molecular Pharmacology | 35 | 29 | |
60 | 1999 | Zn2+ modulation of neuronal transient K+ current: Fast and selective binding to the deactivated channels | Chung-Chin Kuo ; Chen F.-P. | Biophysical Journal | 17 | 18 | |