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.National Taiwan University / 國立臺灣大學
Project / 研究計畫
To Develop Lung Cancer Cell Selection Platform for Studying Cancer Cell Gene Expression and Its Possible Applications
To Develop Lung Cancer Cell Selection Platform for Studying Cancer Cell Gene Expression and Its Possible Applications
Details
Primary Data
Project title
開發肺癌細胞篩選平台探討癌細胞基因表現及其臨床應用
Internal ID
NSTC112-2314-B002-226-MY3
Principal Investigator
KE-CHENG CHEN
Start Date
August 1, 2024
End Date
July 31, 2025
Investigators
Young, Tai-Horng
Organizations
Surgery
Partner Organizations
National Science and Technology Council
Description
Keywords
Lung cancer
cancer cells
selection platform
gene expression
chitosan
Description
本計畫的目標將分三年進行: 第一年(目標一):建立人類肺癌細胞初代細胞培養模型,探討因酸鹼改變而區分細胞之差異,例如細胞活性表現、轉移潛力及侵襲能力。 第二年(目標二):探討因幾丁聚醣(Chitosan)酸鹼敏感性區分之癌細胞基因表現 (如EGFR突變),預期用此平台區分癌細胞之特性與基因表現,並與臨床做比較。 第三年(目標三):建立藥物篩選平台,將酸鹼敏感性區分之癌細胞進行藥物篩選,並探討其臨床應用。
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