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.National Taiwan University / 國立臺灣大學
Project / 研究計畫
Metabolomic Profile and Signature of Exercise Outcomes in Patients with Metabolic Dysfunction-Associated Fatty Liver Disease
Metabolomic Profile and Signature of Exercise Outcomes in Patients with Metabolic Dysfunction-Associated Fatty Liver Disease
Details
Primary Data
Project title
代謝異常脂肪肝患者, 與運動結果相關的代謝體學特徵以及角色探討
Internal ID
NSTC113-2314-B002-241
Principal Investigator
CHUN-JEN LIU
Start Date
August 1, 2024
End Date
July 31, 2025
Organizations
Internal Medicine
Partner Organizations
National Science and Technology Council
Description
Keywords
Metabolic syndrome
fatty liver
exercise intervention
gut microbiota
metabolomics
Description
代謝症候群是重要文明疾病,造成全身很多器官組織的損傷包括代謝異常相關肝疾病(MAFLD),過去稱之為非酒精性脂肪肝 (NAFLD)。代謝體(metabolomics)極有可能影響MAFLD患者之臨床表現,並且可能協助預測MAFLD的臨床預後。本計畫將能建立脂肪肝患者的血漿代謝質體學,釐清運動對脂肪肝患者血漿代謝質體學的影響,以及代謝質體學對對脂肪肝患者的臨床角色,包括脂肪肝嚴重度評估以及運動成效的預測。成果將能提升國內學術水準並對未來相關族群臨床照護與指引建立有所助益。
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