An automated microfluidic platform integrating dual-mode microchannel and localized surface plasmon resonance sensing for multi-parallel biomolecule detection
Journal
22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
Journal Volume
2
Pages
1174-1176
Date Issued
2018
Author(s)
Abstract
We designed a dual-mode microchannel integrating an automated microfluidic platform and localized surface plasmon resonance (LSPR) sensing for multi-parallel biomolecule detection. The platform consists of three components: (1) a four-channel microchannel, which can switch into the synchronized or independent modes based on different assay steps; (2) a microfluidic platform, which can automatically control all reagents flow; and (3) a LSPR spectroscopy system, which performs label-free, real-time, and multi-parallel detection of biomolecules at multiple sensing sites. Based on the above features, we believe that our platform can potentially be used for rapid multi-analyte biomolecule detection for timely disease diagnosis and treatments. Copyright ? (2018) by Chemical and Biological Microsystems Society. All rights reserved.
Subjects
Localized Surface Plasmon Resonance (LSPR); Microfluidics; Multi-parallel Biomolecule Detection
Other Subjects
Biomolecules; Diagnosis; Microchannels; Microfluidics; Plasmons; Resonance; Biomolecule detection; Disease diagnosis; Independent mode; Localized surface plasmon resonance; Microfluidic platforms; Parallel detection; Reagents flows; Three component; Surface plasmon resonance
Type
conference paper