Synthesis, bifunctionalization, and remarkable adsorption performance of benzene-bridged periodic mesoporous organosilicas functionalized with high loadings of carboxylic acids
Journal
Chemistry - A European Journal
Journal Volume
19
Journal Issue
20
Pages
6358-6367
Date Issued
2013
Author(s)
Abstract
Highly ordered benzene-bridged periodic mesoporous organosilicas (PMOs) that were functionalized with exceptionally high loadings of carboxylic acid groups (COOH), up to 80 mol % based on silica, have been synthesized and their use as adsorbents for the adsorption of methylene blue (MB), a basic dye pollutant, and for the loading and release of doxorubicin (DOX), an anticancer drug, is demonstrated. These COOH-functionalized benzene-silicas were synthesized by the co-condensation of 1,4-bis(triethoxysilyl) benzene (BTEB) and carboxyethylsilanetriol sodium salt (CES), an organosilane that contained a carboxylic acid group, in the presence of non-ionic oligomeric surfactant Brij 76 in acidic medium. The materials thus obtained were characterized by a variety of techniques, including powder X-ray diffraction (XRD), nitrogen-adsorption/ desorption isotherms, TEM, and 13C and 29Si solid-state NMR spectroscopy. Owing to the exceptionally high loadings of COOH groups, their high surface areas, and possible π-π-stacking interactions, these adsorbents have very high adsorption capacities and extremely rapid adsorption rates for MB removal and for the controlled loading/release of DOX, thus manifesting their great potential for environmental and biomedical applications. Copyright ? 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Subjects
Biomedical applications; Doxorubicin; High adsorption capacity; Methylene Blue; Periodic mesoporous organosilicas; Periodic mesoporous organosilicas (PMOs); Powder X ray diffraction; Solid-state NMR spectroscopy; Adsorption; Aromatic compounds; Benzene; Drug delivery; Medical applications; Mesoporous materials; Nuclear magnetic resonance spectroscopy; Oligomers; Silica; X ray diffraction; Carboxylic acids; benzene derivative; carboxylic acid; doxorubicin; methylene blue; organosilicon derivative; adsorption; article; chemical model; chemistry; drug delivery system; nuclear magnetic resonance spectroscopy; porosity; synthesis; X ray diffraction; Adsorption; Benzene Derivatives; Carboxylic Acids; Doxorubicin; Drug Delivery Systems; Magnetic Resonance Spectroscopy; Methylene Blue; Models, Chemical; Organosilicon Compounds; Porosity; X-Ray Diffraction
Type
journal article